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Anti-Cancer Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

Review Article

Managing Cancer Treatment in Patients with Renal Dysfunction: The Role of Chemotherapy

Author(s): Ziba Aghsaeifard and Reza Alizadeh*

Volume 23, Issue 16, 2023

Published on: 19 July, 2023

Page: [1811 - 1818] Pages: 8

DOI: 10.2174/1871520623666230602143525

Price: $65

Abstract

Malignancy is characterized by damage to several vital organs, and utilizing chemotherapy as a treatment option can have toxic effects on healthy body tissues. Kidney function is commonly compromised by cancer and chemotherapy. These effects can be pre-renal, intrarenal, or postrenal. Tumor lysis syndrome and electrolyte disturbances are also common in this group of patients. Etiologies of this dysfunction are poorly understood; therefore, careful monitoring and management of renal function are required in such cases. This narrative review aimed to highlight some of the common renal abnormalities among patients receiving cancer and chemotherapy.

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