Microcantilever (MCL) Biosensing

Title: Microcantilever (MCL) Biosensing

Volume: 2 Issue: 3

Author(s): Xiaodong Yan, Hai-Feng Ji and Thomas Thundat

Affiliation:

Keywords: Resonance frequency, Biosensors, DNA microarrays, DNA hybridization, Immobilization, mono-clonal antibody

Abstract: The analytical community continues to search for cost-effective, reliable, and even portable analytical techniques that can give reliable and fast-response results for a variety of biochemicals. Advances in the field of microelectro- mechanical systems (MEMS) and their uses now offer unique opportunities in the design of ultrasensitive analytical devices. Microcantilevers (MCLs) have been emerged as a novel unique platform for label-free biosensor or bioassay. This short review summarizes the biosensors using microcantilever (MCL) technology. DNA-based, antibody-based, enzyme- based, and membrane-based MCL sensors are discussed. The review is intended to provide an experts in this field an overview of MCL biosensors and to help the non-experts in the field to acquire a good understanding of the development of MCL biosensors and the main issues to be considered for further development of this biosensor technique.

Cite this article as:

Yan Xiaodong, Ji Hai-Feng and Thundat Thomas, Microcantilever (MCL) Biosensing, Current Analytical Chemistry 2006; 2 (3) . https://dx.doi.org/10.2174/157341106777698251