[1]
Ma Y, Frutos-Beltrán E, Kang D, Pannecouque C, De Clercq E. *, Menéndez-Arias L*, Liu X*, Zhan P*. Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses. Chem Soc Rev 2021; 50(7): 4514-40.
[2]
Gao S, Sylvester K, Song L, et al. *, Müller CE*, Liu X*, Zhan P*. Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity. J Med Chem 2022; 65(19): 13343-64.
[3]
Zhao T, Zhang J, Tao Y, et al. *, Liu X*, Zhan P*. Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable Druggability. J Med Chem 2022; 65(5): 4218-37.
[4]
Sun L, Dick A, Meuser ME, et al. *, Lee KH*, Liu X*, Zhan P*. Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities. J Med Chem 2020; 63(9): 4790-810.
[5]
Zhao T, Meng Q, Sun Z, et al. *, Liu X*, Zhan P*. Novel Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Favorable Druggability. J Med Chem 2020; 63(19): 10829-54.
[6]
Ju H, Murugan NA, Hou L, et al. *, Huang B*, Liu X*, Zhan P*. Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability. J Med Chem 2021; 64(24): 17992-8009.
[7]
Kang D, Feng D, Sun Y, et al. *, Liu X*, Zhan P*. Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties. J Med Chem 2020; 63(9): 4837-48.
[8]
Kang D, Ruiz FX, Feng D, et al. *, Liu X*, Zhan P*. Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel. J Med Chem 2020; 63(3): 1298-312.
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