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Current Pharmaceutical Biotechnology

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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Review Article

Involvement of Metabolites and Non-coding RNAs in Diseases

Author(s): Kubra A. Coskun, Bercem Yeman Kıyak, Kezban Ucar Cifci, Elif Kadioglu, Nazlican Yurekli and Yusuf Tutar*

Volume 24, Issue 7, 2023

Published on: 10 November, 2022

Page: [889 - 912] Pages: 24

DOI: 10.2174/1389201023666220921091240

Price: $65

Abstract

Non-coding RNAs have a role in gene regulation and cellular metabolism control. Metabolism produces metabolites which are small molecules formed during the metabolic process. So far, a direct relationship between metabolites and genes is not fully established; however, pseudogenes and their progenitor genes regulate health and disease states. Other non-coding RNAs also contribute to this regulation at different cellular processes. Accumulation and depletion of metabolites accompany the dynamic equilibrium of health and disease state. In this study, metabolites, their roles in the cell, and the link between metabolites and non-coding RNAs are discussed.

Keywords: Metabolism, Metabolites, Metabolite analysis, Non-coding, RNAs, disease.

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