Recent Advances in Chitosan-Based Composite Materials in Organic Transformations
- A Review

Kummari   Subba Venkata Krishna   Rao; Kasula      Nagaraja; Boddu      Adilakshmi; Jangam      Lakshmidevi; Guddety   Viswanatha   Reddy; Sung   Soo   Han; Kummara   Madhusudana   Rao
doi:10.2174/1385272826666220908120319
Abstract

Chitosan (CS) is a crustacean-derived bio-macromolecular base. Physico-chemical properties of CS resemble cellulose, and the chemical structure constitutes β-(1-4)-linked Dglucosamine and N-acetyl-D-glucosamine units. It has tunable characteristics such as molecular weight, degree of acetylation, and acetyl distribution. It is proven to be a good support in making catalysts and functional materials. This article comprises the recently published articles using CS-based composites as heterogeneous catalysts in numerous chemical transformations of industrial relevance. In this connection, the CS-based composite materials have been successfully used as heterogeneous catalysts in a wide range of organic transformations, including cycloaddition, trimethylsilylation, cyanation, Suzuki-Miyaura, Heck, Beckmann rearrangement, O-carboxymethylation, nitroarenes reduction, nucleophilic acylation (phenyl acetates from acid chlorides), Knoevenagel condensation, biomass valorization, P–O bond formation, imination, dipolar addition, and multicomponent reactions. The CS has also been used to prepare magnetic nanocompositebased catalysts that showed easy separation and high reusability. This article is highly helpful in designing further chemical transformations where the role of the bio-polymeric base, CS may be critical.
Keywords: Chitosan, Bio-macromolecular base, Composite materials, Heterogeneous catalyst, Organic transformations, Cycloaddition, Suzuki-Miyaura coupling, Heck reaction.
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DOI https://dx.doi.org/10.2174/1385272826666220908120319	Print ISSN 1385-2728
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