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Current Drug Delivery

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ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

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Mini-Review Article

Research Progress of Plant Active Ingredients in Pharmaceutical Cocrystal

Author(s): Zimeng Wang, Hongzhou Shang, Linghuan Gao and Ning Qiao*

Volume 20, Issue 10, 2023

Published on: 23 September, 2022

Page: [1405 - 1424] Pages: 20

DOI: 10.2174/1567201819666220820115950

Price: $65

Abstract

The disadvantages of active ingredients extracted from medicinal plants due to poor solubility in the body and low bioavailability limit their clinical application. Pharmaceutical cocrystal as a new type of drug in solid form has attracted the attention of researchers. This article reviews the effects of cocrystal in various poorly soluble herbal active ingredients of medicinal plants on their physicochemical properties and biological properties and provides references for the application of pharmaceutical cocrystal in poorly soluble active compounds of medicinal plants.

Keywords: Herbal ingredients, pharmaceutical cocrystals, properties solubility, bioavailability, plants, medicinal.

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Graphical Abstract

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