Recent Advances in Biological Active Sulfonamide based Hybrid
Compounds Part B: Two-Component Sulfonamide Hybrids

Shakila      Ghomashi; Reihane      Ghomashi; Hamidreza      Aghaei; Ahmad   Reza   Massah
doi:10.2174/0929867329666220722143547
Abstract

Sulfonamide compounds, also known as sulfa drugs, are a significant class of synthetic bacteriostatic antimicrobials and were the primary source of therapy against bacterial infections before the introduction of penicillin in 1941. Hybridization of sulfonamides with various pharmaceutically active heterocyclic moieties leads to sulfonamide hybrids with a wide variety of biological activities. Part B of this review presents the most recent advances in designing and developing more two-component sulfonamide hybrids containing triazole, thiadiazole, triazine, oxazole/ benzoxazole, isoxazole, oxadiazole, imidazole, benzimidazole, furan, benzofuran, thiophene, pyrrole, indazole, tetrazole, chromene/ chromone, pyridazine, quinoxaline, acridine, phthalazine, and xanthone between 2015 and 2020. We hope this review helps the scientific community in designing more useful sulfonamide hybrid drugs.
Keywords: Sulfonamides, two-component, hybrids, biological activity, bacteriostatic antimicrobials, hybridization.
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DOI https://dx.doi.org/10.2174/0929867329666220722143547	Print ISSN 0929-8673
Publisher Name Bentham Science Publisher	Online ISSN 1875-533X
Current Medicinal Chemistry

Recent Advances in Biological Active Sulfonamide based Hybrid Compounds Part B: Two-Component Sulfonamide Hybrids

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