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Current Pharmaceutical Biotechnology

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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Review Article

Noncoding RNA Databases

Author(s): Jens Allmer*

Volume 24, Issue 7, 2023

Published on: 02 September, 2022

Page: [825 - 831] Pages: 7

DOI: 10.2174/1570180819666220520124511

Price: $65

Abstract

Diseases such as cancer are often defined by dysregulation of gene expression. Noncoding RNAs (ncRNA) such as microRNAs are involved in gene expression and cell-cell communication. Many other ncRNAs exist, such as circular RNAs and small nucleolar RNAs. A wealth of knowledge is available for many ncRNAs, but the information is federated in many databases. A small number of highly complementary ncRNA databases are discussed in this work. Their relevance for cancer research is highlighted, and some of the current problems and limitations are revealed. A central or shared database enforcing community reporting and quality standards is needed in the future.

• RNA-seq

• Noncoding RNAs

• Databases

• Data repositories

Keywords: RNA-seq, noncoding RNAs, databases, data repositories, regulatory RNA, cancer RNAs.

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