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Mini-Reviews in Organic Chemistry

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ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

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Review Article

An Insight on the Potential of Manganese Porphyrins in Cancer Treatment

Author(s): Pankaj Kumar Chaurasia*, Shashi Lata Bharati*, Sunita Singh and Sudha Yadava

Volume 20, Issue 5, 2023

Published on: 29 August, 2022

Page: [483 - 493] Pages: 11

DOI: 10.2174/1570193X19666220427111016

Price: $65

Abstract

Porphyrin ligands are recognized for their special tendency to form metal porphyrin complexes of pronounced value. Such metal porphyrin complexes display promising roles as catalysts in various fields, viz., conversion reactions, oxidation reactions, organic synthesis, pharmaceutical areas, biological and environmental fields, and many more. Out of different metal porphyrins, manganese porphyrins are one of the appreciated metal porphyrins due to their valuable catalytic application and potential in cancer treatment. Herein, the proficient contribution of manganese porphyrins to the treatment of cancer along with the molecular pathways involved have been assessed based on the recent scientific literature available.

Keywords: Manganese porphyrins, molecular pathways, mechanism, cancer treatment, radiation therapy, Manganese porphyrin (MnP)/ascorbate system, cancer cells.

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