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Current Nutrition & Food Science

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ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

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Mini-Review Article

Hypoalbuminemia Caused by Malnutrition and Total Joint Arthroplasties: A Narrative Review

Author(s): Leonardo Henrique Bertolucci*, Samantha Souza de Almeida, Yasmin Podlasinski da Silva, Eduarda Correa Freitas and Carlos Roberto Galia

Volume 19, Issue 1, 2023

Published on: 15 July, 2022

Page: [22 - 31] Pages: 10

DOI: 10.2174/1573401318666220414092533

Price: $65

Abstract

Background: Albumin is the most abundant soluble protein in plasma, and it is a widely used and low-cost marker for the diagnosis of malnutrition. The serum albumin level below 35 g/L defines hypoalbuminemia.

Objective: This review aims to discuss the role of albumin in the body, review hypoalbuminemia associated with postoperative complications in total joint arthroplasty surgeries, and examine the impact of nutritional interventions in malnutrition patients submitted to total joint arthroplasty.

Methods: This article is a narrative review of the literature.

Results: Preoperative hypoalbuminemia has been identified as the only significant predictor for surgical site infection and delayed wound healing after total joint arthroplasty. The postoperative complications related to hypoalbuminemia are infection of the surgical site, pneumonia, length of hospital stay, reintervention, and death. As a result, hypoalbuminemia is also associated with a higher cost of hospitalization for patients.

Conclusion: Hypoalbuminemia and malnutrition are causes of postoperative complications of hip arthroplasty, and the control of these conditions can lead to better results in the postoperative period.

Keywords: Hypoalbuminemia, total joint arthroplasty, surgical site infection, periprosthetic joint infection, malnutrition, postoperative complications.

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Graphical Abstract

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