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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Mini-Review Article

A Mini-Review on Pyridazine Analogs: Chemical and Pharmacological Potentials

Author(s): Saad Alghamdi and Mohammad Asif*

Volume 20, Issue 2, 2023

Published on: 17 June, 2022

Page: [100 - 123] Pages: 24

DOI: 10.2174/1570193X19666220329155551

Price: $65

Abstract

The pyridazinone derivatives have diverse biological potential and are easily synthesized. Due to this, researchers and chemists have paid attention to the design and development of novel and effective bioactive compounds. The substituted pyridazines have shown a wide range of pharmacological activities, such as analgesic, anti-inflammatory, antibacterial, antifungal, anticonvulsant, antidepressant, antianxiety, antitubercular, anti-malarial, anticancer, anti-HIV, platelet inhibitory, hypotensive, cardiotonic, etc. In the current circumstances, it can be concluded that pyridazinone derivatives have great prospects, which remain to be revealed.

Keywords: Chemistry, pyridazine, antibacterial, antifungal, anticonvulsant, anti-malarial, anticancer, biological activities.

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Graphical Abstract

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