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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Similarity Analysis of Protein Sequences Based on the Normalized Relative-Entropy

Author(s): Chun Li, Jun Wang and Yi Zhang

Volume 11, Issue 6, 2008

Page: [477 - 481] Pages: 5

DOI: 10.2174/138620708784911500

Price: $65

Abstract

Based on the classification of 20 amino acids, we reduce a protein primary sequence to six (0,1) sequences. For each of them, two so-called normalized relative-entropies are calculated and thus a 12-D vector is constructed to describe the protein primary sequence. The examination of similarities/dissimilarities among eight different proteins illustrates the utility of the approach.

Keywords: Protein, (0,1)-sequence, normalized relative-entropy


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