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Current Drug Delivery

Editor-in-Chief

ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

Review Article

Liposome Nanoparticles as a Novel Drug Delivery System for Therapeutic and Diagnostic Applications

Author(s): Yanan Meng, Xia Niu and Guiling Li*

Volume 20, Issue 1, 2023

Published on: 10 June, 2022

Page: [41 - 56] Pages: 16

DOI: 10.2174/1567201819666220324093821

Price: $65

Abstract

Liposome nanoparticles (LNPs), as a promising platform in drug delivery, combine the advantages of both liposomes and inorganic/organic nanoparticles into a single system. Both liposomes and nanoparticles have demonstrated optimized drug efficacy in the clinic. LNPs are proven to be multifunctional systems and thus utilized in various research applications (e.g., spatiotemporal control of drug release, hyperthermia, photothermal therapy, and biological imaging). The type of nanoparticles involved in LNPs largely affects the features of LNPs. Besides, diverse nanoparticles enable liposomes to overcome the defects such as poor stability, few functions, and rapid elimination from blood circulation. In this review, multiple nanoparticles materials and further prepared LNPs as well as their structure, physicochemical properties, manipulation and the latest applications in biomedical field are introduced. Future directions in advancing of LNPs are also discussed in the end.

Keywords: Liposome nanoparticles, nanostructure, drug delivery system, controlled drug release, combination therapy, imaging.

Graphical Abstract

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