Abstract
Background: Corona virus is a contagious single-strand RNA virus affecting majorly the lungs causing severe acute respiratory disease. The viral pandemic has affected the world economy and posed new challenges to the scientific community. Due to high mutation rate, a lot of variants are occurring and persons who are vaccinated are also getting affected. In addition, vaccination trials for children aged below 18 are still going on. Moreover, the cost, shelf-life, success rate, no booster dose required, and the long-term complications associated with the vaccine are yet to be studied. Preservation and transportation of vaccines are another big challenge.
Objective: Despite vaccination, the best alternative is to boost our immune system by administration of bioactive compounds which are safe and effective. Bioactive compounds have been found to be effective against several viral infections.
Methods: Literature review has been performed using recently published research and review articles pertaining to the role of plant-derived bioactive compounds in regulating COVID-19 infection.
Result: The current review will describe the role and mechanism of bioactive compounds derived from natural sources in disease management and boosting the immune system against COVID-19.
Conclusion: In addition to vaccination, the administration of plant-derived bioactive compounds will help in regulating viral infection and boosting the immune response during COVID-19 infection.
Keywords: Anti-viral agents, bioactive compounds, COVID-19, immunity, infection, virus.
Graphical Abstract
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