Highly Efficient, Reusable, Functionalized Pyridinium Salts as a Catalyst for the Simple and Cost-effective Preparation of Tetrahydro [b] Benzopyran Derivatives

Title:Highly Efficient, Reusable, Functionalized Pyridinium Salts as a Catalyst for the Simple and Cost-effective Preparation of Tetrahydro [b] Benzopyran Derivatives

Volume: 9 Issue: 3

Author(s): Saida Benzerka, Mohamed Abdenour Redouane, Naima Khiri-Meribout*Abdelmadjid Debache

Affiliation:

• Department of Chemistry, Faculty of Exact Sciences, University of Mentouri Brothers Constantine 1, Constantine, Algeria

Keywords: Multicomponent reaction, one-pot synthesis, tetrahydrobenzo[b]pyrans, pyridinium salts, and ionic liquids

Abstract:

Background: In this work, a series of pyridinium-based ionic liquids (PBILs) were synthesized.

Methods: Pyridinium-based ionic liquids (PBILs) were synthesized through a simple method, which were initially evaluated as catalysts for the synthesis of tetrahydro[b]benzopyran derivatives via a one-pot three-component reaction involving aldehydes, malononitrile, and dimedone.

Results: The PBILs perform well in this condensation reaction, especially 1-methylpyridin-1-ium dimethyl phosphate (MPDMP).

Conclusion: The advantages of this procedure are good yields, short reaction time, simplicity of implementation, and inexpensive starting materials.

Cite this article as:

Benzerka Saida, Redouane Abdenour Mohamed, Khiri-Meribout Naima*, Debache Abdelmadjid, Highly Efficient, Reusable, Functionalized Pyridinium Salts as a Catalyst for the Simple and Cost-effective Preparation of Tetrahydro [b] Benzopyran Derivatives, Current Organocatalysis 2022; 9 (3) . https://dx.doi.org/10.2174/2213337209666220217112937