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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Review Article

Recent Developments in the Synthesis of Bicyclic Condensed Pyrimidinones

Author(s): Rayees Ahmad Naikoo, Rupesh Kumar, Vipan Kumar and Gaurav Bhargava*

Volume 26, Issue 2, 2022

Published on: 31 January, 2022

Page: [122 - 161] Pages: 40

DOI: 10.2174/1385272826666220112152330

Price: $65

Abstract

Functionalized bicyclic pyrimidinones and their derivatives are significant heterocyclic scaffolds being their all-around prevalence in biologically potent compounds. In several attempts to explore the different synthetic methodologies for the construction of bicyclic condensed pyrimidinones, different researchers from all across the globe have reported numerous substantial methods. In the present review, considerable work has been critically compiled on the synthesis of substituted and functionalized bicyclic pyrimidinones from 2000 onwards.

Keywords: Bicyclic pyrimidinones, fused heterocycles, condensed pyrimidinones, heterocycles, Nitrogen heterocycles, biologically active heterocycles.

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Graphical Abstract

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