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Current Respiratory Medicine Reviews

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ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

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Short Communication

Outcomes of Liver Transplantation from Deceased Donors with Coronavirus- Disease 2019 and Late Complications of Infection

Author(s): Mohsen Aliakbarian, Rozita Khodashahi *, Kambiz Akhavan Rezayat , Seyed Mousal-Reza Hosseini, Ebrahim Khaleghi and Soheila Milani

Volume 18, Issue 1, 2022

Published on: 27 January, 2022

Page: [4 - 7] Pages: 4

DOI: 10.2174/1573398X17666211209153335

Price: $65

Abstract

Background: The transplant patients should be considered a main high-risk population during the COVID-19 outbreak due to the use of immunosuppressive regimens and comorbidities.

Objective: This study aimed to evaluate the possibility of COVID-19 transmission by liver transplantation from a donor with a late complication of COVID-19 to the recipients.

Methods: This descriptive study was conducted on all the recipients of liver transplantation who had an acute liver failure or were the models for the End-Stage Liver Disease (MELD) higher than 20.

Results: In general, 36 liver transplantation was performed during the study period. Out of these patients, only 14 cases (deceased donors) had hemorrhagic cerebrovascular accidents, and other donors died of trauma (n=7) and anoxia (n=15). All patients showed negative results for polymerase chain reaction (PCR) (two negative 24 h PCR), whereas their high-resolution computed tomography (HRCT) test revealed that they had previously lung involvement with COVID-19 as the late complication of the disease.

Conclusion: This study supports the safety of continuing donation and transplant process during the outbreak even the transplant donor be infected previously with the COVID-19, which is reinforced by other similar pieces of evidence.

Keywords: Brain death, covid-19, donors, liver transplantation, complications, infection.

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