Generic placeholder image

Recent Advances in Anti-Infective Drug Discovery

Editor-in-Chief

ISSN (Print): 2772-4344
ISSN (Online): 2772-4352

Review Article

Cosmeceutical Aptitudes of Niacinamide: A Review

Author(s): Piyush Madaan, Priyanshi Sikka and Deepinder Singh Malik*

Volume 16, Issue 3, 2021

Published on: 16 December, 2021

Page: [196 - 208] Pages: 13

DOI: 10.2174/2772434416666211129105629

Price: $65

Abstract

Background: The prevalence and scope of dermatological illness differ from region to region. Based upon type and severity, the conditions may vary from superficial to deep systemic skin infections. Niacinamide, an amide analog of vitamin B3 which was conventionally utilized as a food supplement, is now explored for the management of skin disorders. Being a powerhouse on its own, it is not stored inside the body naturally and has to be acquired from external sources.

Areas Covered: This review is an attempt to disclose the physiology, pharmacology, and highlight the dermatological potentials of niacinamide, discussing its pharmacological mechanisms, varied commercially available treatments, and novel approaches, i.e., in research and patented formulations.

Results: Niacinamide has been verified in treating almost every skin disorder, viz. aging, hyperpigmentation, acne, psoriasis, pruritus, dermatitis, fungal infections, epidermal melasma, non-melanoma skin cancer, etc. It has been reported to possess numerous properties, for instance, anti-inflammatory, antimicrobial, antioxidant, antipruritic, and anticancer, which makes it an ideal ingredient for varied dermal therapies. Long term use of niacinamide, regardless of the skin type, paves the way for new skin cells, making skin healthier, brighter, and hydrated.

Conclusion: Niacinamide possesses a variety of positive characteristics in the field of dermatology. Novel approaches are warranted over current treatments which could bypass the above shortcomings and form an effective and stable system. Hence, niacinamide has the potential to become an individual and a productive component with wide future scope.

Keywords: Co-crystals, dermatological disorders, nanoparticles, niacinamide, non-melanoma skin cancer, patents.

Graphical Abstract

[1]
Forbat E, Al-Niaimi F, Ali FR. Use of nicotinamide in dermatology. Clin Exp Dermatol 2017; 42(2): 137-44.
[http://dx.doi.org/10.1111/ced.13021] [PMID: 28052374]
[2]
Rolfe HM. A review of nicotinamide: Treatment of skin diseases and potential side effects. J Cosmet Dermatol 2014; 13(4): 324-8.
[http://dx.doi.org/10.1111/jocd.12119] [PMID: 25399625]
[3]
Chen AC, Damian DL. Nicotinamide and the skin. Australas J Dermatol 2014; 55(3): 169-75.
[http://dx.doi.org/10.1111/ajd.12163] [PMID: 24635573]
[4]
Bissett DL, Miyamoto K, Sun P, Li J, Berge CA. Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. Int J Cosmet Sci 2004; 26(5): 231-8.
[http://dx.doi.org/10.1111/j.1467-2494.2004.00228.x] [PMID: 18492135]
[5]
Bhattaccharjee S, Beck-Broichsitter M, Banga AK. In situ gel formation in microporatedskin for enhanced topical delivery of niacinamide. Pharmaceutics 2020; 12(5): 472.
[http://dx.doi.org/10.3390/pharmaceutics12050472] [PMID: 32455797]
[6]
Sharma L, Agarwal G, Kumar A. Medicinal plants for skin and hair care. Indian J Tradit Knowl 2003; 2(1): 62-8.
[7]
Kotnala A, Verma K, Sharma A, Parashar S, Rathi B, Kumar R. Indian medicinal plants for skin care and cosmeceuticals: A review. J Biomed Ther Sci 2019; 6: 24-60.
[8]
Bhardwaj S, Parashar S, Verma K, Arora R, Chhikara BS. Evaluation of awareness about beauty products composition and proper utilization among college students. Integr J Soc Sci 2019; 6(2): 57-64.
[9]
Otte N, Borelli C, Korting HC. Nicotinamide - biologic actions of an emerging cosmetic ingredient. Int J Cosmet Sci 2005; 27(5): 255-61.
[http://dx.doi.org/10.1111/j.1467-2494.2005.00266.x] [PMID: 18492206]
[10]
Wohlrab J, Kreft D. Niacinamide - mechanisms of action and its topical use in dermatology. Skin Pharmacol Physiol 2014; 27(6): 311-5.
[http://dx.doi.org/10.1159/000359974] [PMID: 24993939]
[11]
Kim NH, Kirsner RS. Nicotinamide in dermatology. Expert Rev Dermatol 2010; 5(1): 23-9.
[http://dx.doi.org/10.1586/edm.09.68]
[12]
Xing X, Liao Z, Tan F, Zhu Z, Jiang Y, Cao Y. Effect of nicotinamide against Candida albicans. Front Microbiol 2019; 10: 595.
[http://dx.doi.org/10.3389/fmicb.2019.00595] [PMID: 30972047]
[13]
Garnaud C, Champleboux M, Maubon D, Cornet M, Govin J. Histone deacetylases and their inhibition in Candida species. Front Microbiol 2016; 7: 1238.
[http://dx.doi.org/10.3389/fmicb.2016.01238] [PMID: 27547205]
[14]
Wurtele H, Tsao S, Lépine G, et al. Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy. Nat Med 2010; 16(7): 774-80.
[http://dx.doi.org/10.1038/nm.2175] [PMID: 20601951]
[15]
Kyme P, Thoennissen NH, Tseng CW, et al. C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice. J Clin Invest 2012; 122(9): 3316-29.
[http://dx.doi.org/10.1172/JCI62070] [PMID: 22922257]
[16]
Dharajiya N, Choudhury BK, Bacsi A, Boldogh I, Alam R, Sur S. Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation. J Allergy Clin Immunol 2007; 119(3): 646-53.
[http://dx.doi.org/10.1016/j.jaci.2006.11.634] [PMID: 17336614]
[17]
Bains P, Kaur M, Kaur J, Sharma S. Nicotinamide: Mechanism of action and indications in dermatology. Indian J Dermatol Venereol Leprol 2018; 84(2): 234-7.
[http://dx.doi.org/10.4103/ijdvl.IJDVL_286_17] [PMID: 29405129]
[18]
Nikas IP, Paschou SA, Ryu HS. The role of nicotinamide in cancer chemoprevention and therapy. Biomolecules 2020; 10(3): 477-96.
[http://dx.doi.org/10.3390/biom10030477] [PMID: 32245130]
[19]
Lin SH, Chong ZZ, Maiese K. Nicotinamide: A nutritional supplement that provides protection against neuronal and vascular injury. J Med Food 2001; 4(1): 27-38.
[http://dx.doi.org/10.1089/10966200152053686] [PMID: 12639285]
[20]
Kim B, Halliday GM, Damian DL. Oral nicotinamide and actinic keratosis: A supplement success story. Curr Probl Dermatol 2015; 46: 143-9.
[http://dx.doi.org/10.1159/000366550] [PMID: 25561219]
[21]
Kolb H, Burkart V. Nicotinamide in type 1 diabetes. Mechanism of action revisited. Diabetes Care 1999; 22(Suppl. 2): B16-20.
[PMID: 10097894]
[22]
Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of niacinamide and niacin. Int J Toxicol 2005; 24(Suppl. 5): 1-31.
[PMID: 16596767]
[23]
Maddukuri S, Devi GL, Metta S, Krishna KM. Development of niacinamide and calendula oil antiacne gel using carrageenans as gelling agents. J Pharm Res 2020; 1(1): 46-52.
[24]
Kim KH, Song PC. Skin care for the performing artist. The singer's guide to complete health 2013. pp: 187.
[25]
Wessels Q, Pretorius E, Smith CM, Nel H. The potential of a niacinamide dominated cosmeceutical formulation on fibroblast activity and wound healing in vitro. Int Wound J 2014; 11(2): 152-8.
[http://dx.doi.org/10.1111/j.1742-481X.2012.01052.x] [PMID: 22892041]
[26]
Boo YC. Mechanistic basis and clinical evidence for the applications of nicotinamide (niacinamide) to control skin aging and pigmentation. Antioxidants 2021; 10(8): 1315.
[http://dx.doi.org/10.3390/antiox10081315] [PMID: 34439563]
[27]
Jerajani HR, Mizoguchi H, Li J, Whittenbarger DJ, Marmor MJ. The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: A randomized, double-blind trial. Indian J Dermatol Venereol Leprol 2010; 76(1): 20-6.
[http://dx.doi.org/10.4103/0378-6323.58674] [PMID: 20061726]
[28]
Crocco EI, Veasey JV, Boin MF, Lellis RF, Alves RO. A novel cream formulation containing nicotinamide 4%, arbutin 3%, bisabolol 1%, and retinaldehyde 0.05% for treatment of epidermal melasma. Cutis 2015; 96(5): 337-42.
[PMID: 26682557]
[29]
Boonme P, Boonthongchuay C, Wongpoowarak W, Amnuaikit T. Evaluation of nicotinamide microemulsion on the skin penetration enhancement. Pharm Dev Technol 2016; 21(1): 116-20.
[http://dx.doi.org/10.3109/10837450.2014.971378] [PMID: 25318786]
[30]
Mehta T. Formulation, characterization, and ex vivo evaluation of microemulsion based gel of nicotinamide. Asian J Pharm 2018; 12(1): 115-21.
[http://dx.doi.org/10.22377/ajp.v12i01.2050]
[31]
Surini S, Mellani T. Formulation and physical evaluation of microemulsion and W/O/W multiple emulsions dosage forms with alpha arbutin, lactic acid, and niacinamide as skin-whitening cosmetics. Int J Appl Pharm 2017; 9: 67-90.
[http://dx.doi.org/10.22159/ijap.2017.v9s1.39_45]
[32]
Orachun T, Wisuitiprot W, Waranuch N. Development of niacinamide loaded-sericin nanoparticle using water in silicone technique. Int Proc Chem Biol Environ Eng 2012; 40: 56-60.
[33]
Huang Y, Zhang B, Gao Y, Zhang J, Shi L. Baicalein-nicotinamide cocrystal with enhanced solubility, dissolution, and oral bioavailability. J Pharm Sci 2014; 103(8): 2330-7.
[http://dx.doi.org/10.1002/jps.24048] [PMID: 24903146]
[34]
Panzade P, Shendarkar G. Design and preparation of zaltoprofen-nicotinamide pharmaceutical cocrystals via liquid assisted grinding method. Indian J Pharm Edu Res 2019; 53(45): S563-70.
[http://dx.doi.org/10.5530/ijper.53.4s.151]
[35]
Yuliandra Y, Zaini E, Syofyan S, et al. Cocrystal of ibuprofen-nicotinamide: Solid-state characterization and in vivo analgesic activity evaluation. Sci Pharm 2018; 86(2): 23-33.
[http://dx.doi.org/10.3390/scipharm86020023] [PMID: 29867030]
[36]
Setyawan D, Sari R, Yusuf H, Primaharinastiti R. Preparation and characterization of artesunate-nicotinamide cocrystal by solvent evaporation and slurry method. Asian J Pharm Clin Res 2014; 7(6): 62-5.
[37]
Del Sole R, Lazzoi MR, Vasapollo G. Synthesis of nicotinamide-based molecularly imprinted microspheres and in vitro controlled release studies. Drug Deliv 2010; 17(3): 130-7.
[http://dx.doi.org/10.3109/10717541003587418] [PMID: 20163194]
[38]
Muyima NY, Zulu G, Bhengu T, Popplewell D. The potential application of some novel essential oils as natural cosmetic preservatives in an aqueous cream formulation. Flavour Fragrance J 2002; 17(4): 258-66.
[http://dx.doi.org/10.1002/ffj.1093]
[39]
Farboud ES, Nasrollahi SA, Tabbakhi Z. Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: In vitro and in vivo studies. Int J Nanomedicine 2011; 6: 611-7.
[http://dx.doi.org/10.2147/IJN.S16815] [PMID: 21674018]
[40]
Tanghetti EA, Kircik LH, Green LJ, et al. A phase 2, multicenter, double-blind, randomized, vehicle-controlled clinical study to compare the safety and efficacy of a novel tazarotene 0.045% lotion and tazarotene 0.1% cream in the treatment of moderate- to-severe acne vulgaris. J Drugs Dermatol 2019; 18(6): 542-8.
[PMID: 31251546]
[41]
Hines J, Wilkinson SM, John SM, et al. The three moments of skin cream application: An evidence-based proposal for use of skin creams in the prevention of irritant contact dermatitis in the workplace. J Eur Acad Dermatol Venereol 2017; 31(1): 53-64.
[http://dx.doi.org/10.1111/jdv.13851] [PMID: 27545662]
[42]
Langevin D. Micelles and microemulsions. Annu Rev Phys Chem 1992; 43: 341-69.
[http://dx.doi.org/10.1146/annurev.pc.43.100192.002013]
[43]
Paul BK, Moulik SP. Microemulsions: An overview. J Dispers Sci Technol 1997; 18(4): 301-67.
[http://dx.doi.org/10.1080/01932699708943740]
[44]
Paul BK, Moulik SP. Uses and applications of microemulsions. Curr Sci 2001; 80(8): 990-1001.
[45]
Schwuger MJ, Stickdorn K, Schomaecker R. Microemulsions in technical processes. Chem Rev 1995; 95(4): 849-64.
[http://dx.doi.org/10.1021/cr00036a003]
[46]
Langevin D. Microemulsions. Acc Chem Res 1988; 21(7): 255-60.
[http://dx.doi.org/10.1021/ar00151a001]
[47]
Friberg SE, Bothorel P. Microemulsions: Structure and dynamics. Boca Raton: CRC Press 1987.
[48]
Mohanraj VJ, Chen Y. Nanoparticles-a review. Trop J Pharm Res 2006; 5(1): 561-73.
[49]
Haase M, Schäfer H. Upconverting nanoparticles. Angew Chem Int Ed Engl 2011; 50(26): 5808-29.
[http://dx.doi.org/10.1002/anie.201005159] [PMID: 21626614]
[50]
De M, Ghosh PS, Rotello VM. Applications of nanoparticles in biology. Adv Mater 2008; 20(22): 4225-41.
[http://dx.doi.org/10.1002/adma.200703183]
[51]
Kittelson DB. Engines and nanoparticles: A review. J Aerosol Sci 1998; 29: 575-88.
[http://dx.doi.org/10.1016/S0021-8502(97)10037-4]
[52]
Yadav AV, Shete AS, Dabke AP, Kulkarni PV, Sakhare SS. Co-crystals: A novel approach to modify physicochemical properties of active pharmaceutical ingredients. Indian J Pharm Sci 2009; 71(4): 359-70.
[http://dx.doi.org/10.4103/0250-474X.57283] [PMID: 20502540]
[53]
Javoor MG, Mondal PK, Chopra D. Cocrystals: A review of recent trends in pharmaceutical and material science applications. Mat Sci Res India 2017; 14(1): 09-18.
[http://dx.doi.org/10.13005/msri/140103]
[54]
Aakery CB, Salmon DJ. Building co-crystals with molecular sense and supramolecular sensibility. CrystEngComm 2005; 7(72): 439-48.
[http://dx.doi.org/10.1039/b505883j]
[55]
Zaworotko M. Crystal engineering of co-crystals and their relevance to pharmaceuticals and solid-state chemistry. Acta Crystallogr C 2008; A64: C11-12.
[http://dx.doi.org/10.1107/S0108767308099637]
[56]
Vishweshwar P, McMahon JA, Bis JA, Zaworotko MJ. Pharmaceutical co-crystals. J Pharm Sci 2006; 95(3): 499-516.
[http://dx.doi.org/10.1002/jps.20578] [PMID: 16444755]
[57]
Aakeröy CB, Chopade PD. Cocrystals: Synthesis, structure, and applications. Supramolecular Chemistry: From Molecules to Nanomaterials NJ, USA: Wiley 2012.
[58]
Korotkova EI, Kratochvíl B. Pharmaceutical cocrystals. Procedia Chem 2014; 10: 473-6.
[http://dx.doi.org/10.1016/j.proche.2014.10.079]
[59]
Chaudhari S, Nikam SA, Khatri N, Wakde S. Co-crystals: A review. J Drug Deliv Ther 2018; 8(65): 350-8.
[http://dx.doi.org/10.22270/jddt.v8i6-s.2194]
[60]
Karimi-Jafari M, Padrela L, Walker GM, Croker DM. Creating cocrystals: A review of pharmaceutical cocrystal preparation routes and applications. Cryst Growth Des 2018; 18(10): 6370-87.
[http://dx.doi.org/10.1021/acs.cgd.8b00933]
[61]
Kadam NR, Suvarna V. Microsphere: A brief review. Asian J Biomed Pharm Sci 2015; 5: 13-9.
[http://dx.doi.org/10.15272/ajbps.v5i47.713]
[62]
Prasad BS, Gupta VR, Devanna N, Jayasurya K. Microspheres as drug delivery system-a review. J Glob Trends Pharm Sci 2014; 5(3): 1961-72.
[63]
Bansal H, Kaur SP, Gupta AK. Microspheres: Methods of preparation and applications: A comparative study. Int J Pharm Sci Rev Res 2011; 10(70): 69-78.
[64]
Prasanth VV, Moy AC, Mathew ST, Mathapan R. Microspheres-an overview. Int J Res Pharm Biomed Sci 2011; 2(2): 332-8.
[65]
Singh C, Purohit S, Singh M, Pandey BL. Design and evaluation of microspheres: A Review. J Drug Deliv Res 2013; 2(2): 18-27.
[66]
Midha K, Nagpal M, Arora S. Microspheres: A recent update. Int J Recent Sci Res 2015; 6(8): 5859-67.
[67]
Mohan ME, Sujitha HA, Rao VU, Ashok M, Kumar AB. A brief review on mucoadhesive microspheres. IJRRPAS 2014; 4(1): 975-86.
[68]
Virmani T, Gupta J. Pharmaceutical application of microspheres: An approach for the treatment of various diseases. Int J Pharm Sci Res 2017; 8(8): 3252-60.
[69]
Sanyal BJ. Substantially dry nicotinamide pads for treatment of skin inflammation. US20140220101A1, 2014.
[70]
Højgaard B, Wittendorff J. Extended release nicotinamide formulation. US10456389B2, 2019.
[71]
Polonka J, Wei X, Bartolone JB. Sunscreen formula vanishing cream. US8119698B2, 2012.
[72]
Sajic D, Breslavets M, Sellitto S. Topical dermatologic acne treatment cream composition and method of manufacture. US20200222358A1, 2020.
[73]
Fitzjarrell EA. Topical spray for treating acne containing niacinamide and NaPCA. US5989523A, 1999.
[74]
Minetti DC. Clear, hydroalcoholic aftershave lotion which moisturizes, conditions, and prevents irritation. US4758599A, 1988.
[75]
Bernstein J. Method and compositions for treatment of acne vulgaris and acne rosacea. US20050169948A1, 2005.
[76]
Dutta M, Kale VS, Nair NS. A skin lightening composition comprising niacinamide and ilomastat. US20180000719A1, 2018.
[77]
Ruey JY, Van Scott EJ. Treatment of psoriasis with nicotinamide analogues. US4258052A, 1981.
[78]
Fitzjarrell E. Exfoliating scrub with niacinamide. US6432430B1, 2002.
[79]
Pero R, Giampapa V. Supplement containing carotenoid, nicotinamide, zinc, water soluble extract of uncaria species and method of the same. US20050287227A1, 2005.

Rights & Permissions Print Cite
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version289msRequest Duration28MBMemory UsageGET article/{article_id}/{param?}Route
  • warninglog[23:20:11] LOG.warning: Optional parameter $article_id declared before required parameter $request i...
  • warninglog[23:20:11] LOG.warning: Function strftime() is deprecated in /home/alphaeurekaselec/public_html/stor...
  • warninglog[23:20:11] LOG.warning: trim(): Passing null to parameter #1 ($string) of type string is deprecated ...
  • warninglog[23:20:11] LOG.warning: Function strftime() is deprecated in /home/alphaeurekaselec/public_html/stor...
  • Booting (89.47ms)time
  • Application (199ms)time
  • 1 x Application (69.03%)
    199ms
    1 x Booting (30.96%)
    89.47ms
    14 templates were rendered
    • articlearticle.blade.php#?blade
    • includes.article_top_bannerarticle_top_banner.blade.php#?blade
    • includes.article_referencearticle_reference.blade.php#?blade
    • export_citation_formexport_citation_form.blade.php#?blade
    • includes.article_bottom_bannerarticle_bottom_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • includes.journal_rightmenujournal_rightmenu.blade.php#?blade
    • includes.journal_right_bannerjournal_right_banner.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET article/{article_id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ArticleController@GetArticleDetails
    namespace
    App\Http\Controllers
    where
    as
    article
    file
    app/Http/Controllers/ArticleController.php:1974-2510
    37 statements were executed, 4 of which were duplicates, 33 unique. Show only duplicated123ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('51803705','',1,1739834411,1739834411) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1739834411
      1.06msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('51803705','/article/119112',1,1739834411,1739834411)
      1.06msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 51803705 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51803705) limit 1
      12.91msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 51803705
      • 1: 51803705
      • 2: 51803705
      • 3: 51803705
      • 4: 51803705
      • 5: 51803705
      • 6: 51803705
      • 7: 51803705
      • 8: 51803705
      • 9: 51803705
      • 10: 51803705
      • 11: 51803705
      • 12: 51803705
      • 13: 51803705
      • 14: 51803705
      • 15: 51803705
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • SELECT at.type_name, p.copyright, p.publisher_location,m.month,y.year, a.publish_on, a.nid article_nid,a.article_id, a.pmid, a.issue_id, a.title, a.abstract,a.podcast,a.altmetric_score,a.altmetric_url,a.kudos_url, a.page_count, a.first_page, a.elocator, a.last_page, i.publication_date, a.file_name, a.file_path, a.doi, a.is_epub,a.epub_type, a.volume_id, a.is_uploaded, a.editor_choice, a.is_epub, j.image_file_name, a.article_no, a.art_type AS article_type, a.supplementary_filename,a.html_filename,a.prc_filename,a.epub_filename, a.graph_abs_lg_filename, a.graph_abs_sm_filename, a.oa_image_lg_filename, a.oa_image_sm_filename, j.journal_banner,a.animated_abstract,a.erratum_in,a.erratum_for, (CASE WHEN a.issue_id =0 THEN j.epub_price ELSE j.price END) AS sell_price, j.epub_price, j.nid AS jour_nid, j.title AS journal_title, j.issn, j.eissn,j.journal_id, j.subtitle AS jour_subtitle, v.volume_id,v.volume_name AS volume, v.year_id, i.title AS issue, i.month_id ,i.type issue_type, j.subtitle,j.formerly_title, ac.subtitle AS epub_title,a.crossmark_enabled,a.text_mining_urls,a.license_urls,a.created, a.receivedate, a.revisedate, a.acceptdate,js.js_title FROM article a LEFT JOIN article_section ac ON a.is_epub = ac.art_sec_id LEFT JOIN journal_section js ON a.js_id = js.js_id LEFT JOIN article_type at ON a.art_type = at.art_type_id LEFT JOIN issue i ON a.issue_id = i.issue_id LEFT JOIN month m ON m.id = i.month_id LEFT JOIN volume v ON v.volume_id = a.volume_id INNER JOIN year y ON y.id = v.year_id INNER JOIN journal j ON j.journal_id = a.journal_id INNER JOIN publisher p ON p.publisher_id = j.publisher_id WHERE a.article_id=119112
      620μsalphaeurekaselec_live_10_06_2022Article.php#408
      Backtrace
      • 11. app/Models/Article.php:408
      • 12. app/Http/Controllers/ArticleController.php:2515
      • 13. app/Http/Controllers/ArticleController.php:2035
      • 14. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 15. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `journal` where `journal_id` = 207 limit 1
      320μsalphaeurekaselec_live_10_06_2022Journal.php#64
      Bindings
      • 0: 207
      Backtrace
      • 14. app/Models/Journal.php:64
      • 15. app/Http/Controllers/ArticleController.php:2516
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=207) and sj.journal_id!=207 group by `j`.`nid`) as `aggregate_table`
      1.22msalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 16. app/Models/Subject.php:200
      • 17. app/Http/Controllers/ArticleController.php:2517
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=207) and sj.journal_id!=207 group by `j`.`nid` order by `j`.`journal_id` asc limit 10 offset 0
      1msalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 14. app/Models/Subject.php:200
      • 15. app/Http/Controllers/ArticleController.php:2517
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=207) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid`) as `aggregate_table`
      5.89msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 16. app/Models/Subject.php:220
      • 17. app/Http/Controllers/ArticleController.php:2518
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=207) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid` order by `v`.`ebook_volume_id` desc limit 10 offset 0
      4.93msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 14. app/Models/Subject.php:220
      • 15. app/Http/Controllers/ArticleController.php:2518
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `keywords` where `article_id` = '119112'
      1.54msalphaeurekaselec_live_10_06_2022Keywords.php#43
      Bindings
      • 0: 119112
      Backtrace
      • 13. app/Models/Keywords.php:43
      • 14. app/Http/Controllers/ArticleController.php:2519
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `article_citation` where `article_id` = '119112'
      2.47msalphaeurekaselec_live_10_06_2022Article.php#1570
      Bindings
      • 0: 119112
      Backtrace
      • 13. app/Models/Article.php:1570
      • 14. app/Http/Controllers/ArticleController.php:2520
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`article_id` = '119112' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      2.09msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 119112
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ArticleController.php:2533
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      210μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2535
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `subtitle` from `journal` where `continues_publication_journal` = 1
      450μsalphaeurekaselec_live_10_06_2022Article.php#1960
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/Article.php:1960
      • 14. app/Http/Controllers/ArticleController.php:2062
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 207 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      33.96msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/ArticleController.php:2068
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 207 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      1.96msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2070
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 207 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      1.28msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2071
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select pdf, html, epub, prc from `article_metrics` where `article_id` = 119112 limit 1
      270μsalphaeurekaselec_live_10_06_2022Article.php#744
      Bindings
      • 0: 119112
      Backtrace
      • 14. app/Models/Article.php:744
      • 15. app/Http/Controllers/ArticleController.php:2091
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from content_by_diseases where content_id = 119112 and content_type = 'article' order by status desc limit 1
      390μsalphaeurekaselec_live_10_06_2022Article.php#751
      Backtrace
      • 11. app/Models/Article.php:751
      • 12. app/Http/Controllers/ArticleController.php:2094
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid article_nid,a.title article_title,j.title journal_title from content_by_diseases cd inner join article a on a.article_id=cd.content_id inner join journal j on j.journal_id=a.journal_id where cd.pid = 16 and cd.sub_disease_id = 475 and content_id!=119112 and cd.content_type = 'article' order by rand() limit 20
      34.53msalphaeurekaselec_live_10_06_2022Article.php#769
      Backtrace
      • 11. app/Models/Article.php:769
      • 12. app/Http/Controllers/ArticleController.php:2098
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `node_meta` where `nid` = 198374 limit 1
      340μsalphaeurekaselec_live_10_06_2022Meta.php#30
      Bindings
      • 0: 198374
      Backtrace
      • 14. app/Models/Meta.php:30
      • 15. app/Http/Controllers/ArticleController.php:2101
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      300μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2108
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `tbl_ht_submission` as `h` where `h`.`subtitle` = 'RAAIDD' and (h.proposal_closing_date = 0 OR TO_DAYS(FROM_UNIXTIME(h.proposal_closing_date)) >= TO_DAYS(NOW())) order by `h`.`manuscript` asc
      350μsalphaeurekaselec_live_10_06_2022Article.php#2025
      Bindings
      • 0: RAAIDD
      Backtrace
      • 13. app/Models/Article.php:2025
      • 14. app/Http/Controllers/ArticleController.php:2112
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '119112' and content_type = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      480μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2186
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '11101' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      410μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2207
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '3056' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      360μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2231
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3056) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3056) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3056)
      2.34msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2272
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 11101) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 11101) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 11101)
      780μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2297
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 119112) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 119112) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51803705 and j.to_ip >=51803705 )) and ((j.from_date <= 1739834411 and j.to_date >= 1739834411 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 119112)
      780μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2329
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `first_page` < '196' and is_uploaded = 1 and issue_id = 11101 order by cast(first_page as SIGNED) desc limit 1
      590μsalphaeurekaselec_live_10_06_2022Article.php#1819
      Bindings
      • 0: 196
      Backtrace
      • 14. app/Models/Article.php:1819
      • 15. app/Http/Controllers/ArticleController.php:2470
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `last_page` > '208' and is_uploaded = 1 and issue_id = 11101 order by cast(first_page as SIGNED) asc limit 1
      550μsalphaeurekaselec_live_10_06_2022Article.php#1831
      Bindings
      • 0: 208
      Backtrace
      • 14. app/Models/Article.php:1831
      • 15. app/Http/Controllers/ArticleController.php:2472
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `language_id` from `multilanguage` where `short_code` = 'en'
      210μsalphaeurekaselec_live_10_06_2022ArticleController.php#2497
      Bindings
      • 0: en
      Backtrace
      • 14. app/Http/Controllers/ArticleController.php:2497
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select `source_lang_label`, `target_lang_label` from `multilanguage_labels` where `target_lang_id` = 1
      270μsalphaeurekaselec_live_10_06_2022MultiLanguage.php#23
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/MultiLanguage.php:23
      • 14. app/Http/Controllers/ArticleController.php:2498
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `id` from `multilanguage_article` where `article_id` = 119112 limit 1
      3.91msalphaeurekaselec_live_10_06_2022ArticleController.php#2506
      Bindings
      • 0: 119112
      Backtrace
      • 16. app/Http/Controllers/ArticleController.php:2506
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 207 and `b`.`banner_from_date` <= 1739834411 and `b`.`banner_to_date` >= 1739834411 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.61msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 207
      • 3: 1739834411
      • 4: 1739834411
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 207 and `b`.`banner_from_date` <= 1739834411 and `b`.`banner_to_date` >= 1739834411 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.57msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 207
      • 3: 1739834411
      • 4: 1739834411
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='50cd00381fa4d44f34895fd9543c80c6'
      300μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\MultiLanguage
    1MultiLanguage.php#?
        _token
        AXpqJkqAPmVk32XLJErrY2OTcUuaQy6Q7i3TPbkb
        uc_cart_id
        50cd00381fa4d44f34895fd9543c80c6
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/article/119112" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /article/119112
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:17 [ "x-https" => array:1 [ 0 => "1" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] "priority" => array:1 [ 0 => "u=0, i" ] "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6IndYdXhieGpWeHppVnFNWHdVMlFaSVE9PSIsInZhbHVlIjoiVUVpTmFjV2xZbkhITS9yY2tqdkxoYUhFY0dlcmdkMzVuSER1clpiK3gwbz0iLCJtYWMiOiJiYjViZjQ0ZWE3YzQ1NTY4NTAxOTYzMjU1NmNjNTFhOTQ4MDYwNjBkNTNkYjMwMTJiZWU2NjAzMGE5NjJmNGRiIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6IndYdXhieGpWeHppVnFNWHdVMlFaSVE9PSIsInZhbHVlIjoiVUVpTmFjV2xZbkhITS9yY2tqdkxoYUhFY0dlcmdkMzVuSER1clpiK3gwbz0iLCJtYWMiOiJiYjViZjQ0ZWE3YzQ1" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Mon, 17 Feb 2025 23:20:11 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IkxyMjBNZk1qcVd4MmYvd0RwOWZOOUE9PSIsInZhbHVlIjoiOFRVVG5HUDl4aW5WUzNoNFl6eFE0NE8zMVF1cUxIM3lCNisrNmdLbXRWKzB5WjRNWFVYVjVrb0RoY3p0UlR6YUwycG8wL2plT0YxU0w2Rm0rOStlTmh4Wm5YSmhMZCtMeWNMWDZGd3lKMTZsZjJrbDZ6eVlQWFVER3NaS0tHdFQiLCJtYWMiOiI2YWJlYmZkMmIwNGM1N2E5MWU2NDQ3OThmMmY2MmI1ZDEyYjNmYmQyNTRlMzAxODljZjg4MmI3MTQ5OGM4MTI4IiwidGFnIjoiIn0%3D; expires=Thu, 20 Feb 2025 11:20:11 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IkxyMjBNZk1qcVd4MmYvd0RwOWZOOUE9PSIsInZhbHVlIjoiOFRVVG5HUDl4aW5WUzNoNFl6eFE0NE8zMVF1cUxIM3lCNisrNmdLbXRWKzB5WjRNWFVYVjVrb0RoY3p0UlR6YUwycG8wL" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ii80NG1jSHRjaUhjdDdvd2pxNEErQ3c9PSIsInZhbHVlIjoiWDA5MkdYWkdJRnVLSFU1SkpqM1c1QXR4ajdyUVFTdThUTTl5NTNSVCttSTdWUDdSRDcvRGlNU1pIVUlqNXgvM2EyYno5SnR5Y0Jva3lYWk41ZHVzUGxwVk5kS2NlazFhNENiSHFQZGxxdDdvMnZYREpKMnNDeHpNdkpBRi8yclIiLCJtYWMiOiI0OGVmOTQ2N2YzOTUxMGQzNGYzOGYxMWNiYjNmY2RhNDJiYThlMGM2ZGI5MzlmZDlmMmI5MjgwNzhhMTFhZmNmIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6Ii80NG1jSHRjaUhjdDdvd2pxNEErQ3c9PSIsInZhbHVlIjoiWDA5MkdYWkdJRnVLSFU1SkpqM1c1QXR4ajdyUVFTdThUTTl5NTNSVCttSTdWUDdSRDcvRGlNU1p" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IkxyMjBNZk1qcVd4MmYvd0RwOWZOOUE9PSIsInZhbHVlIjoiOFRVVG5HUDl4aW5WUzNoNFl6eFE0NE8zMVF1cUxIM3lCNisrNmdLbXRWKzB5WjRNWFVYVjVrb0RoY3p0UlR6YUwycG8wL2plT0YxU0w2Rm0rOStlTmh4Wm5YSmhMZCtMeWNMWDZGd3lKMTZsZjJrbDZ6eVlQWFVER3NaS0tHdFQiLCJtYWMiOiI2YWJlYmZkMmIwNGM1N2E5MWU2NDQ3OThmMmY2MmI1ZDEyYjNmYmQyNTRlMzAxODljZjg4MmI3MTQ5OGM4MTI4IiwidGFnIjoiIn0%3D; expires=Thu, 20-Feb-2025 11:20:11 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IkxyMjBNZk1qcVd4MmYvd0RwOWZOOUE9PSIsInZhbHVlIjoiOFRVVG5HUDl4aW5WUzNoNFl6eFE0NE8zMVF1cUxIM3lCNisrNmdLbXRWKzB5WjRNWFVYVjVrb0RoY3p0UlR6YUwycG8wL" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ii80NG1jSHRjaUhjdDdvd2pxNEErQ3c9PSIsInZhbHVlIjoiWDA5MkdYWkdJRnVLSFU1SkpqM1c1QXR4ajdyUVFTdThUTTl5NTNSVCttSTdWUDdSRDcvRGlNU1pIVUlqNXgvM2EyYno5SnR5Y0Jva3lYWk41ZHVzUGxwVk5kS2NlazFhNENiSHFQZGxxdDdvMnZYREpKMnNDeHpNdkpBRi8yclIiLCJtYWMiOiI0OGVmOTQ2N2YzOTUxMGQzNGYzOGYxMWNiYjNmY2RhNDJiYThlMGM2ZGI5MzlmZDlmMmI5MjgwNzhhMTFhZmNmIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6Ii80NG1jSHRjaUhjdDdvd2pxNEErQ3c9PSIsInZhbHVlIjoiWDA5MkdYWkdJRnVLSFU1SkpqM1c1QXR4ajdyUVFTdThUTTl5NTNSVCttSTdWUDdSRDcvRGlNU1p" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "AXpqJkqAPmVk32XLJErrY2OTcUuaQy6Q7i3TPbkb" "uc_cart_id" => "50cd00381fa4d44f34895fd9543c80c6" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/article/119112" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-17 23:20:11GET/article/119112414371