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Current Neuropharmacology

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ISSN (Print): 1570-159X
ISSN (Online): 1875-6190

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Review Article

Treatment of Circadian Rhythm Sleep–Wake Disorders

Author(s): Shi-Yu Sun and Gui-Hai Chen*

Volume 20, Issue 6, 2022

Published on: 30 March, 2022

Page: [1022 - 1034] Pages: 13

DOI: 10.2174/1570159X19666210907122933

Price: $65

Abstract

Circadian rhythm sleep-wake disorders (CRSWDs) are a distinct class of sleep disorders caused by alterations to the circadian time-keeping system, its entrainment mechanisms, or a mismatch between the endogenous circadian rhythm and the external environment. The main clinical manifestations are insomnia and excessive daytime sleepiness that often lead to clinically meaningful distress or cause mental, physical, social, occupational, educational, or other functional impairment. CRSWDs are easily mistaken for insomnia or early waking up, resulting in inappropriate treatment. CRSWDs can be roughly divided into two categories, namely, intrinsic CRSWDs, in which sleep disturbances are caused by alterations to the endogenous circadian rhythm system due to chronic changes in the regulation or capture mechanism of the biological clock, and extrinsic circadian rhythm sleep-wake disorders, in which sleep disorders, such as jet lag or shift-work disorder, result from environmental changes that cause a mismatch between sleep-wakefulness times and internal circadian rhythms. Sleep diaries, actigraphy, and determination of day and night phase markers (dim light melatonin onset and core body temperature minimum) have all become routine diagnostic methods for CRSWDs. Common treatments for CRSWD currently include sleep health education, time therapy, light therapy, melatonin, and hypnotic drug therapy. Here, we review the progress in the epidemiology, etiology, diagnostic evaluation, diagnostic criteria, and treatment of intrinsic CRSWD, with emphasis on the latter, in the hope of bolstering the clinical diagnosis and treatment of CRSWDs.

Keywords: Circadian rhythm, sleep-wake disorders, etiology, diagnostic evaluation, treatments, melatonin.

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[1]
Lee, R.; Balick, M.J. Chronobiology: it’s about time. Explore (NY), 2006, 2(5), 442-445.
[http://dx.doi.org/10.1016/j.explore.2006.06.022] [PMID: 16979109]
[2]
Duffy, J.F.; Cain, S.W.; Chang, A.M.; Phillips, A.J.; Münch, M.Y.; Gronfier, C.; Wyatt, J.K.; Dijk, D.J.; Wright, K.P., Jr; Czeisler, C.A. Sex difference in the near-24-hour intrinsic period of the human circadian timing system. Proc. Natl. Acad. Sci. USA, 2011, 108(Suppl. 3), 15602-15608.
[http://dx.doi.org/10.1073/pnas.1010666108] [PMID: 21536890]
[3]
Gachon, F.; Nagoshi, E.; Brown, S.A.; Ripperger, J.; Schibler, U. The mammalian circadian timing system: from gene expression to physiology. Chromosoma, 2004, 113(3), 103-112.
[http://dx.doi.org/10.1007/s00412-004-0296-2] [PMID: 15338234]
[4]
Saper, C.B.; Scammell, T.E.; Lu, J. Hypothalamic regulation of sleep and circadian rhythms. Nature, 2005, 437(7063), 1257-1263.
[http://dx.doi.org/10.1038/nature04284] [PMID: 16251950]
[5]
Archer, S.N.; Carpen, J.D.; Gibson, M.; Lim, G.H.; Johnston, J.D.; Skene, D.J.; von Schantz, M. Polymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder. Sleep, 2010, 33(5), 695-701.
[http://dx.doi.org/10.1093/sleep/33.5.695] [PMID: 20469812]
[6]
Kalmbach, D.A.; Schneider, L.D.; Cheung, J.; Bertrand, S.J.; Kariharan, T.; Pack, A.I.; Gehrman, P.R. Genetic basis of chronotype in humans: Insights from three landmark GWAS. Sleep, 2017, 40(2)zsw048
[http://dx.doi.org/10.1093/sleep/zsw048] [PMID: 28364486]
[7]
von Schantz, M. Phenotypic effects of genetic variability in human clock genes on circadian and sleep parameters. J. Genet., 2008, 87(5), 513-519.
[http://dx.doi.org/10.1007/s12041-008-0074-7] [PMID: 19147940]
[8]
Dijk, D.J.; Czeisler, C.A. Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans. J. Neurosci., 1995, 15(5 Pt 1), 3526-3538.
[http://dx.doi.org/10.1523/JNEUROSCI.15-05-03526.1995] [PMID: 7751928]
[9]
Mouret, J.; Coindet, J.; Debilly, G.; Chouvet, G. Suprachiasmatic nuclei lesions in the rat: alterations in sleep circadian rhythms. Electroencephalogr. Clin. Neurophysiol., 1978, 45(3), 402-408.
[http://dx.doi.org/10.1016/0013-4694(78)90191-8] [PMID: 79478]
[10]
Borbély, A.A. A two process model of sleep regulation. Hum. Neurobiol., 1982, 1(3), 195-204.
[PMID: 7185792]
[11]
Münch, M.Y.; Cain, S.W.; Duffy, J.F. Biological Rhythms Workshop IC: sleep and rhythms. Cold Spring Harb. Symp. Quant. Biol., 2007, 72, 35-46.
[http://dx.doi.org/10.1101/sqb.2007.72.065] [PMID: 18419261]
[12]
International Classification of Sleep Disorders, 3rd ed; , 2014.
[13]
Wyatt, J.K. Delayed sleep phase syndrome: pathophysiology and treatment options. Sleep, 2004, 27(6), 1195-1203.
[http://dx.doi.org/10.1093/sleep/27.6.1195] [PMID: 15532214]
[14]
Schrader, H.; Bovim, G.; Sand, T. The prevalence of delayed and advanced sleep phase syndromes. J. Sleep Res., 1993, 2(1), 51-55.
[http://dx.doi.org/10.1111/j.1365-2869.1993.tb00061.x] [PMID: 10607071]
[15]
Hazama, G.I.; Inoue, Y.; Kojima, K.; Ueta, T.; Nakagome, K. The prevalence of probable delayed-sleep-phase syndrome in students from junior high school to university in Tottori, Japan. Tohoku J. Exp. Med., 2008, 216(1), 95-98.
[http://dx.doi.org/10.1620/tjem.216.95] [PMID: 18719343]
[16]
Sivertsen, B.; Pallesen, S.; Stormark, K.M.; Bøe, T.; Lundervold, A.J.; Hysing, M. Delayed sleep phase syndrome in adolescents: prevalence and correlates in a large population based study. BMC Public Health, 2013, 13, 1163.
[http://dx.doi.org/10.1186/1471-2458-13-1163] [PMID: 24330358]
[17]
Paine, S.J.; Fink, J.; Gander, P.H.; Warman, G.R. Identifying advanced and delayed sleep phase disorders in the general population: a national survey of New Zealand adults. Chronobiol. Int., 2014, 31(5), 627-636.
[http://dx.doi.org/10.3109/07420528.2014.885036] [PMID: 24548144]
[18]
Patke, A.; Murphy, P.J.; Onat, O.E.; Krieger, A.C.; Özçelik, T.; Campbell, S.S.; Young, M.W. Mutation of the human circadian clock gene CRY1 in familial delayed sleep phase disorder. Cell, 2017, 169(2), 203-215.e13.
[http://dx.doi.org/10.1016/j.cell.2017.03.027] [PMID: 28388406]
[19]
Aoki, H.; Ozeki, Y.; Yamada, N. Hypersensitivity of melatonin suppression in response to light in patients with delayed sleep phase syndrome. Chronobiol. Int., 2001, 18(2), 263-271.
[http://dx.doi.org/10.1081/CBI-100103190] [PMID: 11379666]
[20]
Richardson, C.E.; Gradisar, M.; Barbero, S.C. Are cognitive “insomnia” processes involved in the development and maintenance of delayed sleep wake phase disorder? Sleep Med. Rev., 2016, 26, 1-8.
[http://dx.doi.org/10.1016/j.smrv.2015.05.001] [PMID: 26140864]
[21]
Auger, R.R.; Burgess, H.J.; Dierkhising, R.A.; Sharma, R.G.; Slocumb, N.L. Light exposure among adolescents with delayed sleep phase disorder: a prospective cohort study. Chronobiol. Int., 2011, 28(10), 911-920.
[http://dx.doi.org/10.3109/07420528.2011.619906] [PMID: 22080736]
[22]
Micic, G.; Lovato, N.; Gradisar, M.; Ferguson, S.A.; Burgess, H.J.; Lack, L.C. The etiology of delayed sleep phase disorder. Sleep Med. Rev., 2016, 27, 29-38.
[http://dx.doi.org/10.1016/j.smrv.2015.06.004] [PMID: 26434674]
[23]
Wyatt, J.K.; Stepanski, E.J.; Kirkby, J. Circadian phase in delayed sleep phase syndrome: predictors and temporal stability across multiple assessments. Sleep, 2006, 29(8), 1075-1080.
[http://dx.doi.org/10.1093/sleep/29.8.1075] [PMID: 16944677]
[24]
Magee, M.; Marbas, E.M.; Wright, K.P., Jr; Rajaratnam, S.M.; Broussard, J.L. Diagnosis, cause, and treatment approaches for delayed sleep-wake phase disorder. Sleep Med. Clin., 2016, 11(3), 389-401.
[http://dx.doi.org/10.1016/j.jsmc.2016.05.004] [PMID: 27542884]
[25]
Keijzer, H.; Smits, M.G.; Duffy, J.F.; Curfs, L.M. Why the dim light melatonin onset (DLMO) should be measured before treatment of patients with circadian rhythm sleep disorders. Sleep Med. Rev., 2014, 18(4), 333-339.
[http://dx.doi.org/10.1016/j.smrv.2013.12.001] [PMID: 24388969]
[26]
Kantermann, T.; Sung, H.; Burgess, H.J. Comparing the morningness- eveningness questionnaire and munich chronotype questionnaire to the dim light melatonin onset. J. Biol. Rhythms, 2015, 30(5), 449-453.
[http://dx.doi.org/10.1177/0748730415597520] [PMID: 26243627]
[27]
Rajaratnam, S.M.; Middleton, B.; Stone, B.M.; Arendt, J.; Dijk, D.J. Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunities in humans. J. Physiol., 2004, 561(Pt 1), 339-351.
[http://dx.doi.org/10.1113/jphysiol.2004.073742] [PMID: 15459246]
[28]
Vandewalle, G.; Middleton, B.; Rajaratnam, S.M.; Stone, B.M.; Thorleifsdottir, B.; Arendt, J.; Dijk, D.J. Robust circadian rhythm in heart rate and its variability: influence of exogenous melatonin and photoperiod. J. Sleep Res., 2007, 16(2), 148-155.
[http://dx.doi.org/10.1111/j.1365-2869.2007.00581.x] [PMID: 17542944]
[29]
Rahman, S.A.; Kayumov, L.; Shapiro, C.M. Antidepressant action of melatonin in the treatment of delayed sleep phase syndrome. Sleep Med., 2010, 11(2), 131-136.
[http://dx.doi.org/10.1016/j.sleep.2009.07.013] [PMID: 20044310]
[30]
Nagtegaal, J.E.; Laurant, M.W.; Kerkhof, G.A.; Smits, M.G.; van der Meer, Y.G.; Coenen, A.M. Effects of melatonin on the quality of life in patients with delayed sleep phase syndrome. J. Psychosom. Res., 2000, 48(1), 45-50.
[http://dx.doi.org/10.1016/S0022-3999(99)00075-6] [PMID: 10750629]
[31]
van Geijlswijk, I.M.; Korzilius, H.P.; Smits, M.G. The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis. Sleep, 2010, 33(12), 1605-1614.
[http://dx.doi.org/10.1093/sleep/33.12.1605] [PMID: 21120122]
[32]
Sletten, T.L.; Magee, M.; Murray, J.M.; Gordon, C.J.; Lovato, N.; Kennaway, D.J.; Gwini, S.M.; Bartlett, D.J.; Lockley, S.W.; Lack, L.C.; Grunstein, R.R.; Rajaratnam, S.M.W. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial. PLoS Med., 2018, 15(6)e1002587
[http://dx.doi.org/10.1371/journal.pmed.1002587] [PMID: 29912983]
[33]
Dahlitz, M.; Alvarez, B.; Vignau, J.; English, J.; Arendt, J.; Parkes, J.D. Delayed sleep phase syndrome response to melatonin. Lancet, 1991, 337(8750), 1121-1124.
[http://dx.doi.org/10.1016/0140-6736(91)92787-3] [PMID: 1674014]
[34]
Dagan, Y.; Yovel, I.; Hallis, D.; Eisenstein, M.; Raichik, I. Evaluating the role of melatonin in the long-term treatment of delayed sleep phase syndrome (DSPS). Chronobiol. Int., 1998, 15(2), 181-190.
[http://dx.doi.org/10.3109/07420529808998682] [PMID: 9562922]
[35]
Mundey, K.; Benloucif, S.; Harsanyi, K.; Dubocovich, M.L.; Zee, P.C. Phase-dependent treatment of delayed sleep phase syndrome with melatonin. Sleep, 2005, 28(10), 1271-1278.
[http://dx.doi.org/10.1093/sleep/28.10.1271] [PMID: 16295212]
[36]
Auger, R.R.; Burgess, H.J.; Emens, J.S.; Deriy, L.V.; Thomas, S.M.; Sharkey, K.M. Clinical practice guideline for the treatment of intrinsic circadian rhythm sleep-wake disorders: advanced sleep-wake phase disorder (ASWPD), delayed sleep-wake phase disorder (DSWPD), non-24-hour sleep-wake rhythm disorder (N24SWD), and irregular sleep-wake rhythm disorder (ISWRD). An update for 2015: An American academy of sleep medicine clinical practice guideline. J. Clin. Sleep Med., 2015, 11(10), 1199-1236.
[http://dx.doi.org/10.5664/jcsm.5100] [PMID: 26414986]
[37]
Hoebert, M.; van der Heijden, K.B.; van Geijlswijk, I.M.; Smits, M.G. Long-term follow-up of melatonin treatment in children with ADHD and chronic sleep onset insomnia. J. Pineal Res., 2009, 47(1), 1-7.
[http://dx.doi.org/10.1111/j.1600-079X.2009.00681.x] [PMID: 19486273]
[38]
Carr, R.; Wasdell, M.B.; Hamilton, D.; Weiss, M.D.; Freeman, R.D.; Tai, J.; Rietveld, W.J.; Jan, J.E. Long-term effectiveness outcome of melatonin therapy in children with treatment-resistant circadian rhythm sleep disorders. J. Pineal Res., 2007, 43(4), 351-359.
[http://dx.doi.org/10.1111/j.1600-079X.2007.00485.x] [PMID: 17910603]
[39]
Crowley, S.J.; Eastman, C.I. Phase advancing human circadian rhythms with morning bright light, afternoon melatonin, and gradually shifted sleep: can we reduce morning bright-light duration? Sleep Med., 2015, 16(2), 288-297.
[http://dx.doi.org/10.1016/j.sleep.2014.12.004] [PMID: 25620199]
[40]
Burke, T.M. Markwald. R.R.; Chinoy, E.D.; Snider, J.A.; Bessman, S.C.; Jung, C.M.; Wright, K.P., Jr. Combination of light and melatonin time cues for phase advancing the human circadian clock. Sleep (Basel), 2013, 36(11), 1617-1624.
[http://dx.doi.org/10.5665/sleep.3110]
[41]
Czeisler, C.A.; Richardson, G.S.; Coleman, R.M.; Zimmerman, J.C.; Moore-Ede, M.C.; Dement, W.C.; Weitzman, E.D. Chronotherapy: resetting the circadian clocks of patients with delayed sleep phase insomnia. Sleep, 1981, 4(1), 1-21.
[http://dx.doi.org/10.1093/sleep/4.1.1] [PMID: 7232967]
[42]
Sharkey, K.M.; Carskadon, M.A.; Figueiro, M.G.; Zhu, Y.; Rea, M.S. Effects of an advanced sleep schedule and morning short wavelength light exposure on circadian phase in young adults with late sleep schedules. Sleep Med., 2011, 12(7), 685-692.
[http://dx.doi.org/10.1016/j.sleep.2011.01.016] [PMID: 21704557]
[43]
Ito, A.; Ando, K.; Hayakawa, T.; Iwata, T.; Kayukawa, Y.; Ohta, T.; Kasahara, Y. Long-term course of adult patients with delayed sleep phase syndrome. Jpn. J. Psychiatry Neurol., 1993, 47(3), 563-567.
[http://dx.doi.org/10.1111/j.1440-1819.1993.tb01800.x] [PMID: 8301870]
[44]
Moldofsky, H.; Musisi, S.; Phillipson, E.A. Treatment of a case of advanced sleep phase syndrome by phase advance chronotherapy. Sleep, 1986, 9(1), 61-65.
[http://dx.doi.org/10.1093/sleep/9.1.61] [PMID: 3961368]
[45]
Oren, D.A.; Wehr, T.A. Hypernyctohemeral syndrome after chronotherapy for delayed sleep phase syndrome. N. Engl. J. Med., 1992, 327(24), 1762.
[http://dx.doi.org/10.1056/NEJM199212103272417] [PMID: 1435929]
[46]
Chang, A.M.; Santhi, N.; St Hilaire, M.; Gronfier, C.; Bradstreet, D.S.; Duffy, J.F.; Lockley, S.W.; Kronauer, R.E.; Czeisler, C.A. Human responses to bright light of different durations. J. Physiol., 2012, 590(13), 3103-3112.
[http://dx.doi.org/10.1113/jphysiol.2011.226555] [PMID: 22526883]
[47]
Santhi, N.; Thorne, H.C.; van der Veen, D.R.; Johnsen, S.; Mills, S.L.; Hommes, V.; Schlangen, L.J.; Archer, S.N.; Dijk, D.J. The spectral composition of evening light and individual differences in the suppression of melatonin and delay of sleep in humans. J. Pineal Res., 2012, 53(1), 47-59.
[http://dx.doi.org/10.1111/j.1600-079X.2011.00970.x] [PMID: 22017511]
[48]
Gooley, J.J.; Rajaratnam, S.M.; Brainard, G.C.; Kronauer, R.E.; Czeisler, C.A.; Lockley, S.W. Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light. Sci. Transl. Med., 2010, 2(31)31ra33
[http://dx.doi.org/10.1126/scitranslmed.3000741] [PMID: 20463367]
[49]
Khalsa, S.B.; Jewett, M.E.; Cajochen, C.; Czeisler, C.A. A phase response curve to single bright light pulses in human subjects. J. Physiol., 2003, 549(Pt 3), 945-952.
[http://dx.doi.org/10.1113/jphysiol.2003.040477] [PMID: 12717008]
[50]
Minors, D.S.; Waterhouse, J.M.; Wirz-Justice, A. A human phase-response curve to light. Neurosci. Lett., 1991, 133(1), 36-40.
[http://dx.doi.org/10.1016/0304-3940(91)90051-T] [PMID: 1791996]
[51]
St Hilaire, M.A.; Gooley, J.J.; Khalsa, S.B.; Kronauer, R.E.; Czeisler, C.A.; Lockley, S.W. Human phase response curve to a 1 h pulse of bright white light. J. Physiol., 2012, 590(13), 3035-3045.
[http://dx.doi.org/10.1113/jphysiol.2012.227892] [PMID: 22547633]
[52]
Schotland, H. Artificial bright light therapy for circadian rhythm sleep-wake disorders. Am. J. Respir. Crit. Care Med., 2019, 200(6), 11-P12.
[http://dx.doi.org/10.1164/rccm.2006P11] [PMID: 31518183]
[53]
Esaki, Y.; Kitajima, T.; Ito, Y.; Koike, S.; Nakao, Y.; Tsuchiya, A.; Hirose, M.; Iwata, N. Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder: An open-label trial. Chronobiol. Int., 2016, 33(8), 1037-1044.
[http://dx.doi.org/10.1080/07420528.2016.1194289] [PMID: 27322730]
[54]
Lack, L.; Bramwell, T.; Wright, H.; Kemp, K. Morning blue light can advance the melatonin rhythm in mild delayed sleep phase syndrome. Sleep Biol. Rhythms, 2007, 5(1), 78-80.
[http://dx.doi.org/10.1111/j.1479-8425.2006.00250.x]
[55]
Alvarez, B.; Dahlitz, M.J.; Vignau, J.; Parkes, J.D. The delayed sleep phase syndrome: clinical and investigative findings in 14 subjects. J. Neurol. Neurosurg. Psychiatry, 1992, 55(8), 665-670.
[http://dx.doi.org/10.1136/jnnp.55.8.665] [PMID: 1527536]
[56]
Richardson, C.; Cain, N.; Bartel, K.; Micic, G.; Maddock, B.; Gradisar, M. A randomised controlled trial of bright light therapy and morning activity for adolescents and young adults with Delayed Sleep-Wake Phase Disorder. Sleep Med., 2018, 45, 114-123.
[http://dx.doi.org/10.1016/j.sleep.2018.02.001] [PMID: 29680419]
[57]
Morin, C.M.; Bootzin, R.R.; Buysse, D.J.; Edinger, J.D.; Espie, C.A.; Lichstein, K.L. Psychological and behavioral treatment of insomnia:update of the recent evidence (1998-2004). Sleep, 2006, 29(11), 1398-1414.
[http://dx.doi.org/10.1093/sleep/29.11.1398] [PMID: 17162986]
[58]
Richardson, C.; Micic, G.; Cain, N.; Bartel, K.; Maddock, B.; Gradisar, M. Cognitive “insomnia” processes in delayed sleep-wake phase disorder: Do they exist and are they responsive to chronobiological treatment? J. Consult. Clin. Psychol., 2019, 87(1), 16-32.
[http://dx.doi.org/10.1037/ccp0000357] [PMID: 30431298]
[59]
Gradisar, M.; Dohnt, H.; Gardner, G.; Paine, S.; Starkey, K.; Menne, A.; Slater, A.; Wright, H.; Hudson, J.L.; Weaver, E.; Trenowden, S. A randomized controlled trial of cognitive-behavior therapy plus bright light therapy for adolescent delayed sleep phase disorder. Sleep, 2011, 34(12), 1671-1680.
[http://dx.doi.org/10.5665/sleep.1432] [PMID: 22131604]
[60]
Danielsson, K.; Jansson-Fröjmark, M.; Broman, J.E.; Markström, A. Cognitive behavioral therapy as an adjunct treatment to light therapy for delayed sleep phase disorder in young adult: a randomized controlled feasibility study. Behav. Sleep Med., 2016, 14(2), 212-232.
[http://dx.doi.org/10.1080/15402002.2014.981817] [PMID: 26244417]
[61]
Takaki, M.; Ujike, H. Aripiprazole is effective for treatment of delayed sleep phase syndrome. Clin. Neuropharmacol., 2014, 37(4), 123-124.
[http://dx.doi.org/10.1097/WNF.0000000000000035] [PMID: 24992089]
[62]
Okawa, M.; Uchiyama, M. Circadian rhythm sleep disorders: characteristics and entrainment pathology in delayed sleep phase and non-24-h sleep-wake syndrome. Sleep Med. Rev., 2007, 11(6), 485-496.
[http://dx.doi.org/10.1016/j.smrv.2007.08.001] [PMID: 17964201]
[63]
Marcus, R.N.; McQuade, R.D.; Carson, W.H.; Hennicken, D.; Fava, M.; Simon, J.S.; Trivedi, M.H.; Thase, M.E.; Berman, R.M. The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study. J. Clin. Psychopharmacol., 2008, 28(2), 156-165.
[http://dx.doi.org/10.1097/JCP.0b013e31816774f9] [PMID: 18344725]
[64]
Omori, Y.; Kanbayashi, T.; Sagawa, Y.; Imanishi, A.; Tsutsui, K.; Takahashi, Y.; Takeshima, M.; Takaki, M.; Nishino, S.; Shimizu, T. Low dose of aripiprazole advanced sleep rhythm and reduced nocturnal sleep time in the patients with delayed sleep phase syndrome: an open-labeled clinical observation. Neuropsychiatr. Dis. Treat., 2018, 14, 1281-1286.
[http://dx.doi.org/10.2147/NDT.S158865] [PMID: 29849459]
[65]
Buxton, O.M.; Frank, S.A.; L’Hermite-Balériaux, M.; Leproult, R.; Turek, F.W.; Van Cauter, E. Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms. Am. J. Physiol., 1997, 273(3 Pt 1), E536-E542.
[PMID: 9316443]
[66]
Barger, L.K.; Wright, K.P., Jr; Hughes, R.J.; Czeisler, C.A. Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2004, 286(6), R1077-R1084.
[http://dx.doi.org/10.1152/ajpregu.00397.2003] [PMID: 15031136]
[67]
Youngstedt, S.D.; Kripke, D.F.; Elliott, J.A. Circadian phase-delaying effects of bright light alone and combined with exercise in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2002, 282(1), R259-R266.
[http://dx.doi.org/10.1152/ajpregu.00473.2001] [PMID: 11742846]
[68]
Gradisar, M.; Crowley, S.J. Delayed sleep phase disorder in youth. Curr. Opin. Psychiatry, 2013, 26(6), 580-585.
[http://dx.doi.org/10.1097/YCO.0b013e328365a1d4] [PMID: 24060912]
[69]
Bartlett, D.J.; Biggs, S.N.; Armstrong, S.M. Circadian rhythm disorders among adolescents: assessment and treatment options. Med. J. Aust., 2013, 199(8), S16-S20.
[http://dx.doi.org/10.5694/mja13.10912] [PMID: 24138360]
[70]
Hida, A.; Kitamura, S.; Mishima, K. Pathophysiology and pathogenesis of circadian rhythm sleep disorders. J. Physiol. Anthropol., 2012, 31(1), 7.
[http://dx.doi.org/10.1186/1880-6805-31-7] [PMID: 22738311]
[71]
Ando, K.; Kripke, D.F.; Ancoli-Israel, S. Delayed and advanced sleep phase symptoms. Isr. J. Psychiatry Relat. Sci., 2002, 39(1), 11-18.
[PMID: 12013705]
[72]
Dagan, Y.; Eisenstein, M. Circadian rhythm sleep disorders: toward a more precise definition and diagnosis. Chronobiol. Int., 1999, 16(2), 213-222.
[http://dx.doi.org/10.3109/07420529909019087] [PMID: 10219492]
[73]
Foley, D.J.; Monjan, A.A.; Brown, S.L.; Simonsick, E.M.; Wallace, R.B.; Blazer, D.G. Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep, 1995, 18(6), 425-432.
[http://dx.doi.org/10.1093/sleep/18.6.425] [PMID: 7481413]
[74]
Toh, K.L.; Jones, C.R.; He, Y.; Eide, E.J.; Hinz, W.A.; Virshup, D.M.; Ptácek, L.J.; Fu, Y.H. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science, 2001, 291(5506), 1040-1043.
[http://dx.doi.org/10.1126/science.1057499] [PMID: 11232563]
[75]
Jones, C.R.; Campbell, S.S.; Zone, S.E.; Cooper, F.; DeSano, A.; Murphy, P.J.; Jones, B.; Czajkowski, L.; Ptácek, L.J. Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans. Nat. Med., 1999, 5(9), 1062-1065.
[http://dx.doi.org/10.1038/12502] [PMID: 10470086]
[76]
Xu, Y.; Padiath, Q.S.; Shapiro, R.E.; Jones, C.R.; Wu, S.C.; Saigoh, N.; Saigoh, K.; Ptácek, L.J.; Fu, Y.H. Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature, 2005, 434(7033), 640-644.
[http://dx.doi.org/10.1038/nature03453] [PMID: 15800623]
[77]
Hirano, A.; Shi, G.; Jones, C.R.; Lipzen, A.; Pennacchio, L.A.; Xu, Y.; Hallows, W.C.; McMahon, T.; Yamazaki, M.; Ptáček, L.J.; Fu, Y.H. A Cryptochrome 2 mutation yields advanced sleep phase in humans. eLife, 2016, 5e16695
[http://dx.doi.org/10.7554/eLife.16695] [PMID: 27529127]
[78]
Yoon, I.Y.; Kripke, D.F.; Elliott, J.A.; Youngstedt, S.D.; Rex, K.M.; Hauger, R.L. Age-related changes of circadian rhythms and sleep-wake cycles. J. Am. Geriatr. Soc., 2003, 51(8), 1085-1091.
[http://dx.doi.org/10.1046/j.1532-5415.2003.51356.x] [PMID: 12890070]
[79]
Morgenthaler, T.; Alessi, C.; Friedman, L.; Owens, J.; Kapur, V.; Boehlecke, B.; Brown, T.; Chesson, A., Jr; Coleman, J.; Lee-Chiong, T.; Pancer, J.; Swick, T.J. Practice parameters for the use of actigraphy in the assessment of sleep and sleep disorders: an update for 2007. Sleep, 2007, 30(4), 519-529.
[http://dx.doi.org/10.1093/sleep/30.4.519] [PMID: 17520797]
[80]
Sack, R.L.; Auckley, D.; Auger, R.R.; Carskadon, M.A.; Wright, K.P., Jr; Vitiello, M.V.; Zhdanova, I.V. Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An American Academy of Sleep Medicine review. Sleep, 2007, 30(11), 1484-1501.
[http://dx.doi.org/10.1093/sleep/30.11.1484] [PMID: 18041481]
[81]
Zee, P.C. Melantonin for the treatment of advanced sleep phase disorder. Sleep, 2008, 31(7), 923.
[PMID: 18652087]
[82]
van den Heuvel, C.J.; Ferguson, S.A.; Macchi, M.M.; Dawson, D. Comment on ‘Melatonin as a hypnotic: pro’. Sleep Med. Rev., 2005, 9(1), 67-68.
[http://dx.doi.org/10.1016/j.smrv.2004.09.002] [PMID: 15649739]
[83]
Andersen, L.P.; Gögenur, I.; Rosenberg, J.; Reiter, R.J. The Safety of melatonin in humans. Clin. Drug Investig., 2016, 36(3), 169-175.
[http://dx.doi.org/10.1007/s40261-015-0368-5] [PMID: 26692007]
[84]
Lack, L.; Wright, H.; Kemp, K.; Gibbon, S. The treatment of early-morning awakening insomnia with 2 evenings of bright light. Sleep, 2005, 28(5), 616-623.
[http://dx.doi.org/10.1093/sleep/28.5.616] [PMID: 16171276]
[85]
Voderholzer, U.; Wirz-Justice, A.; Demisch, L.; Berger, M.; Riemann, D. Case report: treatment of a patient with sleep phase advance disorder with phototherapy. Wien. Med. Wochenschr., 1995, 145(17-18), 470-472.
[PMID: 8588371]
[86]
Abbott, S.M.; Reid, K.J.; Zee, P.C. Circadian rhythm sleep-wake disorders. Psychiatr. Clin. North Am., 2015, 38(4), 805-823.
[http://dx.doi.org/10.1016/j.psc.2015.07.012] [PMID: 26600110]
[87]
Suhner, A.G.; Murphy, P.J.; Campbell, S.S. Failure of timed bright light exposure to alleviate age-related sleep maintenance insomnia. J. Am. Geriatr. Soc., 2002, 50(4), 617-623.
[http://dx.doi.org/10.1046/j.1532-5415.2002.50154.x] [PMID: 11982660]
[88]
Palmer, C.R.; Kripke, D.F.; Savage, H.C., Jr; Cindrich, L.A.; Loving, R.T.; Elliott, J.A. Efficacy of enhanced evening light for advanced sleep phase syndrome. Behav. Sleep Med., 2003, 1(4), 213-226.
[http://dx.doi.org/10.1207/S15402010BSM0104_4] [PMID: 15602801]
[89]
Münch, M.; Scheuermaier, K.D.; Zhang, R.; Dunne, S.P.; Guzik, A.M.; Silva, E.J.; Ronda, J.M.; Duffy, J.F. Effects on subjective and objective alertness and sleep in response to evening light exposure in older subjects. Behav. Brain Res., 2011, 224(2), 272-278.
[http://dx.doi.org/10.1016/j.bbr.2011.05.029] [PMID: 21664380]
[90]
Meesters, Y.; van Houwelingen, C.A. Rapid mood swings after unmonitored light exposure. Am. J. Psychiatry, 1998, 155(2), 306.
[PMID: 9464218]
[91]
Hayakawa, T.; Uchiyama, M.; Kamei, Y.; Shibui, K.; Tagaya, H.; Asada, T.; Okawa, M.; Urata, J.; Takahashi, K. Clinical analyses of sighted patients with non-24-hour sleep-wake syndrome: a study of 57 consecutively diagnosed cases. Sleep, 2005, 28(8), 945-952.
[http://dx.doi.org/10.1093/sleep/28.8.945] [PMID: 16218077]
[92]
Lockley, S.W.; Skene, D.J.; Butler, L.J.; Arendt, J. Sleep and activity rhythms are related to circadian phase in the blind. Sleep, 1999, 22(5), 616-623.
[http://dx.doi.org/10.1093/sleep/22.5.616] [PMID: 10450596]
[93]
Leger, D.; Guilleminault, C.; Defrance, R.; Domont, A.; Paillard, M. Prevalence of sleep/wake disorders in persons with blindness. Clin. Sci. (Lond.), 1999, 97(2), 193-199.
[http://dx.doi.org/10.1042/CS19990004] [PMID: 10409474]
[94]
Flynn-Evans, E.E.; Tabandeh, H.; Skene, D.J.; Lockley, S.W. Circadian rhythm disorders and melatonin production in 127 blind women with and without light perception. J. Biol. Rhythms, 2014, 29(3), 215-224.
[http://dx.doi.org/10.1177/0748730414536852] [PMID: 24916394]
[95]
Hankins, M.W.; Peirson, S.N.; Foster, R.G. Melanopsin: an exciting photopigment. Trends Neurosci., 2008, 31(1), 27-36.
[http://dx.doi.org/10.1016/j.tins.2007.11.002] [PMID: 18054803]
[96]
Lockley, S.W.; Dressman, M.A.; Licamele, L.; Xiao, C.; Fisher, D.M.; Flynn-Evans, E.E.; Hull, J.T.; Torres, R.; Lavedan, C.; Polymeropoulos, M.H. Tasimelteon for non-24-hour sleep-wake disorder in totally blind people (SET and RESET): two multicentre, randomised, double-masked, placebo-controlled phase 3 trials. Lancet, 2015, 386(10005), 1754-1764.
[http://dx.doi.org/10.1016/S0140-6736(15)60031-9] [PMID: 26466871]
[97]
Sack, R.L.; Brandes, R.W.; Kendall, A.R.; Lewy, A.J. Entrainment of free-running circadian rhythms by melatonin in blind people. N. Engl. J. Med., 2000, 343(15), 1070-1077.
[http://dx.doi.org/10.1056/NEJM200010123431503] [PMID: 11027741]
[98]
Lewy, A.J.; Bauer, V.K.; Hasler, B.P.; Kendall, A.R.; Pires, M.L.; Sack, R.L. Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin. Brain Res., 2001, 918(1-2), 96-100.
[http://dx.doi.org/10.1016/S0006-8993(01)02964-X] [PMID: 11684046]
[99]
Hoban, T.M.; Sack, R.L.; Lewy, A.J.; Miller, L.S.; Singer, C.M. Entrainment of a free-running human with bright light? Chronobiol. Int., 1989, 6(4), 347-353.
[http://dx.doi.org/10.3109/07420528909056941] [PMID: 2627721]
[100]
Oren, D.A.; Giesen, H.A.; Wehr, T.A. Restoration of detectable melatonin after entrainment to a 24-hour schedule in a ‘free-running’ man. Psychoneuroendocrinology, 1997, 22(1), 39-52.
[http://dx.doi.org/10.1016/S0306-4530(96)00038-8] [PMID: 9141150]
[101]
Watanabe, T.; Kajimura, N.; Kato, M.; Sekimoto, M.; Hori, T.; Takahashi, K. Case of a non-24 h sleep-wake syndrome patient improved by phototherapy. Psychiatry Clin. Neurosci., 2000, 54(3), 369-370.
[http://dx.doi.org/10.1046/j.1440-1819.2000.00719.x] [PMID: 11186118]
[102]
Hayakawa, T.; Kamei, Y.; Urata, J.; Shibui, K.; Ozaki, S.; Uchiyama, M.; Okawa, M. Trials of bright light exposure and melatonin administration in a patient with non-24 hour sleep-wake syndrome. Psychiatry Clin. Neurosci., 1998, 52(2), 261-262.
[http://dx.doi.org/10.1111/j.1440-1819.1998.tb01064.x] [PMID: 9628185]
[103]
Yanagihara, M.; Nakamura, M.; Usui, A.; Nishida, S.; Ito, E.; Okawa, M.; Inoue, Y. The melatonin receptor agonist is effective for free-running type circadian rhythm sleep disorder: case report on two sighted patients. Tohoku J. Exp. Med., 2014, 234(2), 123-128.
[http://dx.doi.org/10.1620/tjem.234.123] [PMID: 25253260]
[104]
Kurita, M.; Moriya, T.; Nishino, S.; Hirata, E.; Hirasawa, N.; Okubo, Y.; Sato, T. Non-24-hour sleep-wake syndrome improved by low-dose valproic acid: a case report. Neuropsychiatr. Dis. Treat., 2016, 12, 3199-3203.
[http://dx.doi.org/10.2147/NDT.S115648] [PMID: 28008257]
[105]
Zee, P.C.; Vitiello, M.V. Circadian rhythm sleep disorder: irregular sleep wake rhythm type. Sleep Med. Clin., 2009, 4(2), 213-218.
[http://dx.doi.org/10.1016/j.jsmc.2009.01.009] [PMID: 20160950]
[106]
Abbott, S.M.; Zee, P.C. Irregular sleep-wake rhythm disorder. Sleep Med. Clin., 2015, 10(4), 517-522.
[http://dx.doi.org/10.1016/j.jsmc.2015.08.005] [PMID: 26568126]
[107]
Okawa, M.; Nanami, T.; Wada, S.; Shimizu, T.; Hishikawa, Y.; Sasaki, H.; Nagamine, H.; Takahashi, K. Four congenitally blind children with circadian sleep-wake rhythm disorder. Sleep, 1987, 10(2), 101-110.
[http://dx.doi.org/10.1093/sleep/10.2.101] [PMID: 3589322]
[108]
Zdanys, K.F.; Steffens, D.C. Sleep disturbances in the elderly. Psychiatr. Clin. North Am., 2015, 38(4), 723-741.
[http://dx.doi.org/10.1016/j.psc.2015.07.010] [PMID: 26600105]
[109]
Kim, J.H.; Duffy, J.F. Circadian rhythm sleep-wake disorders in older adults. Sleep Med. Clin., 2018, 13(1), 39-50.
[http://dx.doi.org/10.1016/j.jsmc.2017.09.004] [PMID: 29412982]
[110]
Pavlova, M. Circadian rhythm sleep-wake disorders. Continuum (Minneap. Minn.), 2017, 23(4), 1051-1063.
[http://dx.doi.org/10.1212/CON.0000000000000499]
[111]
Takaesu, Y.; Komada, Y.; Inoue, Y. Melatonin profile and its relation to circadian rhythm sleep disorders in Angelman syndrome patients. Sleep Med., 2012, 13(9), 1164-1170.
[http://dx.doi.org/10.1016/j.sleep.2012.06.015] [PMID: 22841843]
[112]
Potocki, L.; Glaze, D.; Tan, D.X.; Park, S.S.; Kashork, C.D.; Shaffer, L.G.; Reiter, R.J.; Lupski, J.R. Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome. J. Med. Genet., 2000, 37(6), 428-433.
[http://dx.doi.org/10.1136/jmg.37.6.428] [PMID: 10851253]
[113]
Jan, J.E.; Espezel, H.; Appleton, R.E. The treatment of sleep disorders with melatonin. Dev. Med. Child Neurol., 1994, 36(2), 97-107.
[http://dx.doi.org/10.1111/j.1469-8749.1994.tb11818.x] [PMID: 8132132]
[114]
Shamir, E.; Laudon, M.; Barak, Y.; Anis, Y.; Rotenberg, V.; Elizur, A.; Zisapel, N. Melatonin improves sleep quality of patients with chronic schizophrenia. J. Clin. Psychiatry, 2000, 61(5), 373-377.
[http://dx.doi.org/10.4088/JCP.v61n0509] [PMID: 10847313]
[115]
Riemersma-van der Lek, R.F.; Swaab, D.F.; Twisk, J.; Hol, E.M.; Hoogendijk, W.J.; Van Someren, E.J. Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. JAMA, 2008, 299(22), 2642-2655.
[http://dx.doi.org/10.1001/jama.299.22.2642] [PMID: 18544724]
[116]
Mishima, K.; Okawa, M.; Hishikawa, Y.; Hozumi, S.; Hori, H.; Takahashi, K. Morning bright light therapy for sleep and behavior disorders in elderly patients with dementia. Acta Psychiatr. Scand., 1994, 89(1), 1-7.
[http://dx.doi.org/10.1111/j.1600-0447.1994.tb01477.x] [PMID: 8140901]
[117]
Ancoli-Israel, S.; Gehrman, P.; Martin, J.L.; Shochat, T.; Marler, M.; Corey-Bloom, J.; Levi, L. Increased light exposure consolidates sleep and strengthens circadian rhythms in severe Alzheimer’s disease patients. Behav. Sleep Med., 2003, 1(1), 22-36.
[http://dx.doi.org/10.1207/S15402010BSM0101_4] [PMID: 15600135]
[118]
Guilleminault, C.; McCann, C.C.; Quera-Salva, M.; Cetel, M. Light therapy as treatment of dyschronosis in brain impaired children. Eur. J. Pediatr., 1993, 152(9), 754-759.
[http://dx.doi.org/10.1007/BF01953995] [PMID: 8223810]
[119]
Buscemi, N.; Vandermeer, B.; Hooton, N.; Pandya, R.; Tjosvold, L.; Hartling, L.; Vohra, S.; Klassen, T.P.; Baker, G. Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis. BMJ, 2006, 332(7538), 385-393.
[http://dx.doi.org/10.1136/bmj.38731.532766.F6] [PMID: 16473858]

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