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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Recent Developments in the Synthesis of Five- and Six-membered N-heterocycles from Dicarbonyl Compounds

Author(s): Navjeet Kaur*, Pranshu Bhardwaj and Mansi Gupta

Volume 25, Issue 22, 2021

Published on: 11 August, 2021

Page: [2765 - 2790] Pages: 26

DOI: 10.2174/1385272825666210812102416

Price: $65

Abstract

Various diketones such as 1,2-diketones, 1,3-diketones, 1,4-diketones, β - diketones and dicarbonyl compounds are used in the synthesis of core heterocyclic compounds such as pyrazoles, isoxazoles, triazoles and quinolones. They play an important role in synthetic organic chemistry. The diketones and dicarbonyl compounds also act as chelating ligands for the lanthanides and a large number of transition metals in material chemistry. 50% of drugs contain nitrogen heterocyclic compounds, so organic chemists have made efforts for the synthesis of nitrogen-containing heterocyclic compounds. This review article has compiled different methodologies for the synthesis of five- and six-membered nitrogencontaining heterocyclic compounds.

Keywords: Synthesis, dicarbonyl compounds, diketones, nitrogen, heterocycles, six-membered.

Graphical Abstract


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