An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anticancer Activity

Title:An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anticancer Activity

Volume: 27 Issue: 43

Author(s): Gowhar Naikoo*, Fatema Al-Mashali, Fareeha Arshad, Naema AL-Maashani, Israr U. Hassan, Zamzam AL-Baraami, Lukmanul H. Faruck *, Ahsanulhaq Qurashi, Waqar Ahmed, Abdullah M. Asiri, Alaa A. Aljabali, Hamid A. Bakshi*Murtaza M. Tambuwala*

Affiliation:

• Department of Mathematics and Sciences, College of Arts and Applied Sciences, Dhofar University, Salalah 211,Oman

• Department of Urology, Masonic Cancer Center, University of Minnesota, MN55455,,United States

• School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland,United Kingdom

• School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland,United Kingdom

Keywords: Cancer, nanomedicine, copper nanoparticles, diagnostics, therapeutics, cancer treatment, nanomaterials.

Abstract: In this review, we summarised the different methods for copper nanoparticle synthesis, including green methods. We highlighted that the synthesis of the copper nanoparticles from green sources is preferable as they serve as stable and reducing entities. Furthermore, we critically reviewed the effectiveness of copper- based nanoparticles in oncogenic treatments emphasizing breast, lung, colorectal, and skin cancers. Finally, we have summarised the recent progress made in copper-based nanoparticles and their applications to amplify and rectify present cancer treatment options. The synthesis, characterization, stabilization, and functionalization techniques of various copper-based nanoparticles have also been highlighted in each section. In conclusion, the review provides the outlook of copper nanoparticles in cancer diagnostics and therapeutics.

Cite this article as:

Naikoo Gowhar *, Al-Mashali Fatema , Arshad Fareeha , AL-Maashani Naema , Hassan U. Israr , AL-Baraami Zamzam , Faruck H. Lukmanul *, Qurashi Ahsanulhaq , Ahmed Waqar, Asiri M. Abdullah , Aljabali A. Alaa , Bakshi A. Hamid *, Tambuwala M. Murtaza *, An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anticancer Activity, Current Pharmaceutical Design 2021; 27 (43) . https://dx.doi.org/10.2174/1381612827666210804100303