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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

The Combinatorial Synthesis of Organophosphorus Compounds

Author(s): Stephen D. Lindell, Bernhard Lesch and Douglas W. Thomson

Volume 11, Issue 1, 2008

Page: [36 - 61] Pages: 26

DOI: 10.2174/138620708783398359

Price: $65

Abstract

The primary literature concerning the combinatorial synthesis of organophosphorus compounds is reviewed and discussed. The subject matter is divided into three main sections describing the solid phase, solution phase and solvent- free synthesis of phosphorus containing organic molecules. The review covers the synthesis of compounds in which the final products contain phosphorus-carbon bonds, primarily phosphonates, phosphinates, phosphine oxides and phosphines.

Keywords: carbonylaminophosphonates, tyrosine phosphatase, Phosphononucleotides, solid phase synthesis, Sulfide, Polymer Supported base


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