Abstract
Background: In the last few decades, nanostructures like nanoparticles, dendrimers, quantum dots, nanotubes, etc., gain significant attention in the field of biomedicine. Recently, various modification techniques were employed for the generation of newly modified nanostructured biomaterials. Nowadays, these biomaterials are exploited for the treatment and diagnosis of various biological disorders.
Objective: The present manuscript aims to describe the various types of nanostructures along with the techniques of modification and their applications in the diagnosis and treatment of biological disorders.
Results and Conclusion: Various modification techniques involved in different reaction methodologies are described in the present manuscript. From the study, it is investigated that the modified nanostructured can be utilized in the diagnosis and treatment of biological disorders. Modification of nanostructured materials introduces superior properties and enables them as the detection tool and treatment kit for biological disorders.
Keywords: Nanomaterials, diagnostic material, nanoformulations, metallic nanoparticles, diagnosis, biomaterials.
Graphical Abstract
[http://dx.doi.org/10.3762/bjnano.9.98] [PMID: 29719757]
[http://dx.doi.org/10.3390/pharmaceutics12060522] [PMID: 32521627]
[http://dx.doi.org/10.1002/adfm.200800662] [PMID: 19946357]
[http://dx.doi.org/10.1002/adem.201900287]
[http://dx.doi.org/10.1177/0883911517720814]
[http://dx.doi.org/10.1007/s40820-018-0226-0] [PMID: 30417005]
[http://dx.doi.org/10.1038/s41598-018-24700-9] [PMID: 29674743]
[http://dx.doi.org/10.1002/9781118359686]
[http://dx.doi.org/10.3390/polym11071160] [PMID: 31288433]
[http://dx.doi.org/10.1021/jacs.8b08648] [PMID: 30689954]
[http://dx.doi.org/10.3390/nano3020242] [PMID: 28348334]
[http://dx.doi.org/10.1016/j.jconrel.2016.11.016] [PMID: 27865853]
[http://dx.doi.org/10.1016/j.actbio.2017.11.003] [PMID: 29109027]
[http://dx.doi.org/10.1016/j.msec.2006.05.029]
[http://dx.doi.org/10.1016/j.compositesb.2019.03.050]
[http://dx.doi.org/10.1007/978-3-540-49661-8_15]
[http://dx.doi.org/10.1016/j.chempr.2019.01.004]
[http://dx.doi.org/10.1016/j.snb.2018.09.017]
[http://dx.doi.org/10.1038/s41598-019-43900-5] [PMID: 31101842]
[http://dx.doi.org/10.1039/C39940000463]
[http://dx.doi.org/10.1080/17435390701882478] [PMID: 20827377]
[http://dx.doi.org/10.1071/EN09123]
[http://dx.doi.org/10.1088/0957-4484/19/34/345605] [PMID: 21730654]
[http://dx.doi.org/10.1021/acsbiomaterials.7b00975]
[http://dx.doi.org/10.1016/j.colsurfb.2018.07.034] [PMID: 30036791]
[http://dx.doi.org/10.1007/1-4020-4741-X_16]
[http://dx.doi.org/10.1016/j.matchemphys.2009.03.007]
[http://dx.doi.org/10.1021/acs.jpcc.6b06486]
[http://dx.doi.org/10.1080/15394451003598395]
[http://dx.doi.org/10.1007/s12274-019-2560-z]
[http://dx.doi.org/10.1021/acs.accounts.7b00063] [PMID: 28485945]
[http://dx.doi.org/10.1021/la8020639] [PMID: 18759505]
[http://dx.doi.org/10.2174/1385272819666150810221009]
[http://dx.doi.org/10.1021/acs.langmuir.8b01784] [PMID: 30011364]
[http://dx.doi.org/10.1038/nmat1505]
[http://dx.doi.org/10.1021/jacs.7b07302] [PMID: 28899098]
[http://dx.doi.org/10.1021/acsnano.6b04358] [PMID: 27598543]
[http://dx.doi.org/10.1021/acs.chemmater.8b03295]
[http://dx.doi.org/10.1021/acs.jpcc.6b10901]
[http://dx.doi.org/10.1021/jacs.7b07434] [PMID: 29094943]
[http://dx.doi.org/10.1021/ja0173167] [PMID: 11916419]
[http://dx.doi.org/10.1021/acs.jpcc.8b08942]
[http://dx.doi.org/10.1038/s41598-019-47262-w] [PMID: 31341232]
[http://dx.doi.org/10.1016/j.bbrc.2006.11.135] [PMID: 17184736]
[http://dx.doi.org/10.1007/s00232-016-9940-z] [PMID: 27933338]
[http://dx.doi.org/10.1080/21691401.2018.1501380] [PMID: 30146920]
[http://dx.doi.org/10.1038/sj.cgt.7700844] [PMID: 15891776]
[http://dx.doi.org/10.1007/s10311-019-00901-0]
[http://dx.doi.org/10.1038/s41585-019-0178-2] [PMID: 30962568]
[http://dx.doi.org/10.4414/smw.2014.13908] [PMID: 24395443]
[http://dx.doi.org/10.1016/j.biomaterials.2007.12.032] [PMID: 18242693]
[http://dx.doi.org/10.1002/adma.201604847] [PMID: 28185336]
[http://dx.doi.org/10.1016/j.nanoen.2015.12.026]
[http://dx.doi.org/10.3390/mi8060194]
[http://dx.doi.org/10.2174/0929867311209024942] [PMID: 22963628]
[http://dx.doi.org/10.1155/2016/5762431]
[http://dx.doi.org/10.1016/j.arabjc.2017.05.011]