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Current Genomics

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ISSN (Print): 1389-2029
ISSN (Online): 1875-5488

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Review Article

Single-cell RNA Sequencing in Immunology

Author(s): Yirui Cao, Yue Qiu, Guowei Tu* and Cheng Yang*

Volume 21, Issue 8, 2020

Page: [564 - 575] Pages: 12

DOI: 10.2174/1389202921999201020203249

Price: $65

Abstract

The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions.

Keywords: Single-cell RNA sequencing, immunology, cancer, autoimmune disease, transplantation, tumors.

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