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Current Drug Therapy

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ISSN (Print): 1574-8855
ISSN (Online): 2212-3903

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Research Article

Evaluation of Drug Use Based on the WHO Prescribing Indicator in Mizan-Tepi University Teaching Hospital, South Western Ethiopia: A Cross-sectional Study

Author(s): Solomon Hambisa*, Rediet Feleke, Ameha Zewudie and Mohammed Yimam

Volume 15, Issue 5, 2020

Page: [518 - 523] Pages: 6

DOI: 10.2174/1574885515999200819092717

Price: $65

Abstract

Background: Rational drug use comprises aspects of prescribing, dispensing, and patient use of medicines for different health problems. This study is aimed to assess drug prescribing practices based on the world health organization prescribing indicators in Mizan-Tepi University teaching hospital.

Methods: An institutional-based, retrospective, cross-sectional study was conducted to evaluate the prescribing practices in Mizan-Tepi University teaching hospital. Data were collected based on the World health organization's drug use indicators using prescription papers. A total of 600 prescriptions, written for a 1-year time, dispensed through the general outpatient pharmacy of the hospital were collected by a systematic random sampling method from Mizan-Tepi University teaching hospital.

Results: The present study found that the average number of drugs per prescription was 2.04 ± 0.87 in Mizan-Tepi University teaching hospital, with a range between 1 and 5. Prescribing by generic name was 97.6%, and 47.8% of prescriptions contained antibiotics in the hospital. 27.7% of prescriptions contained at least one injectable medication in Mizan-Tepi University teaching hospital. From prescribed drugs, 96.7% of them were prescribed from the Ethiopian essential drug list.

Conclusion: Present study indicated that the average number of drugs prescribed per encounter, the percentage of generic prescribing, and prescribing from the EDL were close to the optimal value. However, the percentage of encounters with antibiotics and injections prescribed was found to be very high. Thus, the study highlights some improvements in prescribing habits, particularly by focusing on the inappropriate consumption of antibiotics and injections.

Keywords: Drug use, prescribing indicators, World Health Organization, Ethiopia, medicine, antibiotics.

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[1]
WHO Medicines Strategy . Framework for Action Essential Drugs and Medicines Policy 2000-2003Geneva: WHO/EDM/2000 2000.
[2]
Ofori-Asenso R, Brhlikova P, Pollock AM. Prescribing indicators at primary health care centers within the WHO African region: a systematic analysis (1995-2015). BMC Public Health 2016; 16: 724.
[http://dx.doi.org/10.1186/s12889-016-3428-8] [PMID: 27545670]
[3]
Tsega B, Makonnen E. Comparative evaluation of drug prescription appropriateness in public and private health institutions of south west Ethiopia: The case of Wolkite Town. Int J Pharm Sci Res 2012; 3(12): 4922-8.
[4]
The use of Essential Drugs. 6th Report of the Expert Committee Geneva: WHO Technical Report Series 8503. 1995.
[5]
WHO. How to investigate drug use in health facilities: Selected drug use indicators. Geneva: WHO/DAP/93.1 1993.
[6]
Laing R, Hogerzeil H, Ross-Degnan D. Ten recommendations to improve use of medicines in developing countries. Health Policy Plan 2001; 16(1): 13-20.
[http://dx.doi.org/10.1093/heapol/16.1.13] [PMID: 11238425]
[7]
WHO The Rational Use of Drugs Report of a conference of experts, Nairobi, 25-29 November 1985. Geneva: WHO 1987.
[8]
Food, Medicine and Healthcare Administration and Control Authority (FMHACA) of Ethiopia. 2nd ed. Addis Ababa: Manual for Medicines Good Prescribing Practice 2012.
[9]
Desalegn AA. Assessment of drug use pattern using WHO prescribing indicators at Hawassa University Teaching and Referral Hospital, south Ethiopia: a cross-sectional study. BMC Health Serv Res 2013; 13: 170.
[http://dx.doi.org/10.1186/1472-6963-13-170] [PMID: 23647871]
[10]
Atif M, Azeem M, Sarwar MR, et al. WHO/INRUD prescribing indicators and prescribing trends of antibiotics in the Accident and Emergency Department of Bahawal Victoria Hospital, Pakistan. Springerplus 2016; 5(1): 1928.
[http://dx.doi.org/10.1186/s40064-016-3615-1] [PMID: 27933228]
[11]
WHO. World Health Organization promoting rational use of medicines: Core components. WHO Policy and Perspectives on medicine no. 5 Document WHO/EDM/2002.3 2002.
[12]
World Health Organization and Health Action International (WHO/HAI) Measuring medicine prices, availability, affordability and price components. 2nd ed. Geneva: WHO/HAI 2008.
[13]
Carasso BS, Lagarde M, Tesfaye A, Palmer N. Availability of essential medicines in Ethiopia: an efficiency-equity trade-off? Trop Med Int Health 2009; 14(11): 1394-400.
[http://dx.doi.org/10.1111/j.1365-3156.2009.02383.x] [PMID: 19754520]
[14]
Summoro TS, Gidebo KD, Kanche ZZ, Woticha EW. Evaluation of trends of drug-prescribing patterns based on WHO prescribing indicators at outpatient departments of four hospitals in southern Ethiopia. Drug Des Devel Ther 2015; 9: 4551-7.
[http://dx.doi.org/10.2147/DDDT.S83588] [PMID: 26309400]
[15]
Dikaso D, Gobe Z, Teklemariam S. A base line survey on prescribing indicators and underlying factors influencing prescribing in southern Ethiopia. Ethiop J Health Dev 1998; 12(2): 87-93.
[16]
Mallet HP, Njikam A, Scouflaire SM. Evaluation of prescription practices and of the rational use of medicines in Niger. Sante 2001; 11(3): 185-93.
[PMID: 11641083]
[17]
Otoom S, Batieha A, Hadidi H, Hasan M, Al Saudi K. Evaluation of drug use in Jordan using WHO prescribing indicators East Mediterr Health J Action programme on Essential drugs and vaccines Managing drug supply West Hartford, Connecticut, USA: Kumarian Press 2002; 8 pp.(4-5): 537-43.
[18]
Action programme on Essential drugs and vaccines Managing drug supply. West Hartford, Connecticut, USA: Kumarian Press 1997.
[19]
Wubetu M, Derebe D, Mulaw T, Yimer T, Hailu G. Assessment of Drug Prescription Pattern in Two District Hospitals, Northwest Ethiopia. J Health Educ Res Dev 2018; 6(1): 246.
[http://dx.doi.org/10.4172/2380-5439.1000246]
[20]
Mensa M, Tadesse T, Ayele A. Assessment of Drug Use Pattern by Using WHO Core Drug Use Indicators at Public Hospitals in Ethiopia. J Community Med Health Educ 2017; 7(5): 559.
[http://dx.doi.org/10.4172/2161-0711.1000559]
[21]
Mariam AH, Raghavendra Y, Mulisa E. Evaluating rational drug use with the help of World Health Organization’s Core indicators in Bule Hora Hospital, Southern Ethiopia. Gaziantep Med J 2015; 21(2): 108-13.
[http://dx.doi.org/10.5455/GMJ-30-1206]
[22]
Assessment of the Pharmaceutical Sector in Ethiopia Addis Ababa 2003. Accessed at http://www.who.int/medicines/areas/coordination/ethiopia_pharmaceutical.pdf
[23]
Aravamuthan A, Arputhavanan M, Subramaniam K, Udaya Chander JS. Assessment of current prescribing practices using World Health Organization core drug use and complementary indicators in selected rural community pharmacies in Southern India. J Pharm Policy Pract 2016; 10: 1.
[http://dx.doi.org/10.1186/s40545-016-0074-6] [PMID: 27446591]
[24]
Pathak A, Gupta VK, Maurya A, Kumar A, Singh A. Assessment of drug prescribing pattern using WHO indicators in hospitalized patients at a tertiary care teaching hospital in rural area of India. Int J Basic Clin Pharmacol 2016; 5(3): 651-5.
[http://dx.doi.org/10.18203/2319-2003.ijbcp20160983]
[25]
Guyon AB, Barman A, Ahmed JU, Ahmed AU, Alam MS. A baseline survey on use of drugs at the primary health care level in Bangladesh. Bull World Health Organ 1994; 72(2): 265-71.
[PMID: 8205647]
[26]
Hamadeh GN, Dickerson LM, Saab BR, Major SC. Common prescriptions in ambulatory care in Lebanon. Ann Pharmacother 2001; 35(5): 636-40.
[http://dx.doi.org/10.1345/aph.10175] [PMID: 11346071]
[27]
Rambhade S, Chakarborty A, Shrivastava A, Patil UK, Rambhade A. A survey on polypharmacy and use of inappropriate medications. Toxicol Int 2012; 19(1): 68-73.
[http://dx.doi.org/10.4103/0971-6580.94506] [PMID: 22736907]
[28]
Lamichhane DC, Giri BR, Pathak OK, Panta OB, Shankar PR. Morbidity profile and prescribing patterns among outpatients in a teaching hospital in Western Nepal. McGill J Med 2006; 9(2): 126-33.
[PMID: 18523618]
[29]
El Mahalli AA. WHO/INRUD drug prescribing indicators at primary health care centres in Eastern province, Saudi Arabia. East Mediterr Health J 2012; 18(11): 1091-6.
[http://dx.doi.org/10.26719/2012.18.11.1091] [PMID: 23301369]
[30]
Mengistu S, Shiferaw G, Ibro A, et al. Assessment of the Pharmaceutical sector in Ethiopia Addis Ababa: Federal democratic republic of Ethiopia Ministry of health, World health organization 2003.
[31]
Awad AI, Himad HA. Drug-use practices in teaching hospitals of Khartoum State, Sudan. Eur J Clin Pharmacol 2006; 62(12): 1087-93.
[http://dx.doi.org/10.1007/s00228-006-0216-x] [PMID: 17091270]
[32]
Christensen RF. A strategy for the improvement of prescribing and drug use in rural health facilities in Uganda 1990. Ugandan essential drugs and management program; How to investigate drug use in health facilities. Geneva: WHO; 1993. 74 (WHO/DAP/93.1).
[33]
Assen A, Abrha S. Assessment of drug prescribing pattern in Dessie referral hospital, Dessie. Int J Pharm Sci Res 2014; 5(11): 777-81.
[34]
Sisay M, Mengistu G, Molla B, et al. Evaluation of rational drug use based on World Health Organization core drug use indicators in selected public hospitals of Eastern Ethiopia: a cross sectional study. BMC Health Serv Res 2017; 17: 161.
[35]
Prasad PS, Rudra JT, Vasanthi P, Sushitha U, Sadiq MJ, Narayana G. Assessment of drug use pattern using World Health Organization core drug use indicators at Secondary Care Referral Hospital of South India. CHRISMED J Health Res 2015; 2(3): 223-8.
[36]
Awad A, Al-Saffar N. Evaluation of drug use practices at primary healthcare centers of Kuwait. Eur J Clin Pharmacol 2010; 66(12): 1247-55.
[http://dx.doi.org/10.1007/s00228-010-0872-8] [PMID: 20669012]
[37]
Karimi A, Haerizadeh M, Soleymani F, Haerizadeh M, Taheri F. Evaluation of medicine prescription pattern using World Health Organization prescribing indicators in Iran: A cross-sectional study. J Res Pharm Pract 2014; 3(2): 39-45.
[http://dx.doi.org/10.4103/2279-042X.137058] [PMID: 25114935]
[38]
Medicines: Rational Use of Medicines Fact sheet No338 WHO 2010.http://www.who.int/mediacentre/factsheets/fs338/en/
[39]
Tripathy JP, Bahuguna P, Prinja S. Drug prescription behavior: a cross-sectional study in public health facilities in two states of North India. Perspect Clin Res 2018; 9(2): 76-82.
[http://dx.doi.org/10.4103/picr.PICR_75_17] [PMID: 29862200]
[40]
The use of essential drugs Seventh report of WHO Expert Committee (including the revised model list of essential drugs). Geneva: WHO 1997.

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