Login Register Cart 0
Generic placeholder image

Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
General Review Article

Epidemiology of the Incidence and Mortality of Pancreas Cancer and its Relationship with the Human Development Index (HDI) in the World: An Ecological Study in 2018

Author(s): Elham Goodarzi, Ali Hassanpour Dehkordi, Reza Beiranvand, Hasan Naemi and Zaher Khazaei*

Volume 26, Issue 40, 2020

Page: [5163 - 5173] Pages: 11

DOI: 10.2174/1381612826666200713170047

Price: $65

Abstract

Objective: Pancreatic cancer is one of the leading causes of mortality in developed countries and a lethal malignant neoplasm worldwide. This study aims to evaluate the epidemiology of pancreatic cancer incidence and mortality and its relationship with HDI.

Methods: This is a descriptive cross-sectional study that is based on cancer incidence data and cancer mortality rates derived from the GLOBOCAN in 2018.

The incidence and mortality rates of Pancreas as well as Pancreas cancer distribution maps were derived for world countries. The data analysis was conducted using a correlation test, and regression tests were used to evaluate the correlation of the incidence and mortality of Pancreas with HDI. The statistical analysis was carried out by Stata-14, and a significance level of 0.05 was considered.

Results: The highest incidence of pancreatic cancer was reported in Asia with 214499 (46.7%) cases and the lowest incidence was related to Oceania with 4529 cases (0.99%). The results showed a positive and significant correlation between incidence (r = 0.764, P <0.0001) and mortality (r = 0.771, P <0.0001) of pancreatic cancer and the HDI index. The results of ANOVA revealed that the highest mean incidence was related to the very high HDI (P <0.0001) and the highest mortality was connected to the very high human development (P <0.0001). The results exhibited that incidence was positively and significantly correlated with GNI (r = 0.497, P <0.0001), MYS (r = 0.746, P <0.0001), LEB (r = 0.676, <0.0001) and EYS (r = 0.738, P <0.0001). Also, a significant positive correlation was found between mortality and GNI (r = 0.507, P <0.0001), MYS (r = 0.745, P <0.0001), LEB (r = 0.679, <0.0001), and EYS (r = 0.748, P <0.0001).

Conclusion: Given the higher incidence and mortality of pancreatic cancer in countries with HDI, it is necessary to pay a greater attention to risk factors and appropriate planning to reduce these factors and minimize the impact and mortality rate of this disease.

Keywords: Incidence, mortality, pancreatic cancer, human development index, world, epidemiology.

« Previous Next »
[1]
Norouzirad R, Khazaei Z, Mousavi M, et al. Epidemiology of common cancers in Dezful county, southwest of Iran. Immunopathologia Persa 2017; 4e318
[http://dx.doi.org/10.15171/ipp.2018.10]
[2]
Are C, Chowdhury S, Ahmad H, et al. Predictive global trends in the incidence and mortality of pancreatic cancer based on geographic location, socio-economic status, and demographic shift. J Surg Oncol 2016; 114(6): 736-42.
[http://dx.doi.org/10.1002/jso.24410] [PMID: 27511902]
[3]
Khazaei Z, Khazaei S, Valizadeh R, et al. The epidemiology of injuries and accidents in children under one year of age, during (2009-2016) in Hamadan Province, Iran. Int J Pediatr 2016; 4: 2213-20.
[4]
Wong MCS, Jiang JY, Liang M, Fang Y, Yeung MS, Sung JJY. Global temporal patterns of pancreatic cancer and association with socioeconomic development. Sci Rep 2017; 7(1): 3165.
[http://dx.doi.org/10.1038/s41598-017-02997-2] [PMID: 28600530]
[5]
Mousavi Movahhed S, Beladi Mousavi S, Hayati F, et al. The relationship between chronic kidney disease and cancer. J Nephropathol 2018; 7: 115-6.
[http://dx.doi.org/10.15171/jnp.2018.26]
[6]
Sierra MS, Soerjomataram I, Antoni S, et al. Cancer patterns and trends in Central and South America. Cancer Epidemiol 2016; 44(Suppl. 1): S23-42.
[http://dx.doi.org/10.1016/j.canep.2016.07.013] [PMID: 27678320]
[7]
Pourhoseingholi MA, Vahedi M, Baghestani AR. Burden of gastrointestinal cancer in Asia; an overview. Gastroenterol Hepatol Bed Bench 2015; 8(1): 19-27.
[PMID: 25584172]
[8]
Fazeli Z. Fazeli Bavandpour Fs, Abdi. A, Pour Hosaingholi M, Bastaminezhad. Trend analysis of pancreatic cancer mortality. J Ilam University Med Sci 2013; 20: 239-45.
[9]
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68(6): 394-424.
[http://dx.doi.org/10.3322/caac.21492] [PMID: 30207593]
[10]
GLOBOCAN. 2018. Available form: http://www.gco.iarc.fr/today/
[11]
Bray F, Jemal A, Grey N, Ferlay J, Forman D. Global cancer transitions according to the Human Development Index (2008-2030): a population-based study. Lancet Oncol 2012; 13(8): 790-801.
[http://dx.doi.org/10.1016/S1470-2045(12)70211-5] [PMID: 22658655]
[12]
Khazaei S, Rezaeian S, Khazaei Z, et al. National Breast cancer mortality and incidence rates according to the human development index: an ecological study. Adv Breast Cancer Res 2016; 5e30
[http://dx.doi.org/10.4236/abcr.2016.51003]
[13]
Programme UND. Human development report 2016. Available from: http://hdr.undp.org/en
[14]
Fidler MM, Soerjomataram I, Bray F. A global view on cancer incidence and national levels of the human development index. Int J Cancer 2016; 139(11): 2436-46.
[http://dx.doi.org/10.1002/ijc.30382] [PMID: 27522007]
[15]
Katanoda K, Yako-Suketomo H. Comparison of time trends in pancreatic cancer mortality (1990-2006) between countries based on the WHO mortality database. Jpn J Clin Oncol 2010; 40(6): 601-2.
[http://dx.doi.org/10.1093/jjco/hyq089] [PMID: 20508075]
[16]
Wang L, Yang G-H, Lu X-H, Huang Z-J, Li H. Pancreatic cancer mortality in China (1991-2000). World J Gastroenterology. WJG 2003; 9e1819
[http://dx.doi.org/10.3748/wjg.v9.i8.1819]
[17]
Tanaka R, Matsuzaka M, Sasaki Y. Influence of income on cancer incidence and death among patients in Aomori, Japan. Asian Pacific J Cancer PrevAPJCP 2018; 19e3193
[18]
Vineis P, Wild CP. Global cancer patterns: causes and prevention. Lancet 2014; 383(9916): 549-57.
[http://dx.doi.org/10.1016/S0140-6736(13)62224-2] [PMID: 24351322]
[19]
Antoni S, Soerjomataram I, Møller B, Bray F, Ferlay J. An assessment of GLOBOCAN methods for deriving national estimates of cancer incidence. Bull World Health Organ 2016; 94(3): 174-84.
[http://dx.doi.org/10.2471/BLT.15.164384] [PMID: 26966328]

Rights & Permissions Print Cite
Article Metrics
17
1
© 2024 Bentham Science Publishers | Privacy Policy