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Endocrine, Metabolic & Immune Disorders - Drug Targets

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ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

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Research Article

Green Synthesis of Copper Oxide Nanoparticles using Cucumis Sativus (Cucumber) Extracts and their Bio-Physical and Biochemical Characterization for Cosmetic and Dermatologic Applications

Author(s): Monika Vats*, Shruti Bhardwaj and Arvind Chhabra*

Volume 21, Issue 4, 2021

Published on: 05 July, 2020

Page: [726 - 733] Pages: 8

DOI: 10.2174/1871530320666200705212107

Price: $65

Abstract

Background & Objective: Nanoparticles are used in cosmetic and dermatologic products, due to better skin penetration properties. Incorporation of natural products exhibiting medicinal properties in nano-preparations could significantly improve the efficacy of these products and improve the quality of life without the side effects of synthetic formulations.

Methods: We here report the green synthesis of Copper Oxide nanoparticles, using Cucumber extract, and their detailed bio-physical and bio-chemical characterization.

Results: These Copper Oxide-Cucumber nanoparticles exhibit significant anti-bacterial and anti-fungal properties, Ultra Violet-radiation protection ability and reactive-oxygen species inhibition properties. Importantly, these nanoparticles do not exhibit significant cellular toxicity and, when incorporated in skin cream, exhibit skin rejuvenating properties.

Conclusion: Our findings have implications for nanoparticle-based cosmetics and dermatologic applications.

Keywords: Nanoparticles, nanotechnology, nano-cosmetics, skin cream, copper oxide, cucumis sativus, cucumber.

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