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Mini-Review Article

抗血管生成剂：血管内皮生长因子受体2（VEGFR-2）抑制剂的综述。

卷 28, 期 13, 2021

发表于: 14 May, 2020

页: [2540 - 2564] 页: 25

弟呕挨: 10.2174/0929867327666200514082425

价格: $65

摘要

可以通过抑制血管生成来实现肿瘤生长的抑制，这是近年来引起人们极大关注的领域。 抑制血管生成的重要靶标包括血管内皮生长因子受体（VEGFR）及其同源酪氨酸激酶受体。 基于抑制VEGFR-2的抗血管生成疗法是一种有效的临床治疗策略。 本文从药物开发和化学合成两个方面综述了VEGFR-2抑制剂的研究进展。

关键词: 肿瘤，抗血管生成剂，酪氨酸激酶，VEGFR-2抑制剂，批准的药物，合成。

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