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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

Pyrazole Carboxylic Acid and Derivatives: Synthesis and Biological Applications

Author(s): Adnan Cetin*

Volume 18, Issue 1, 2021

Published on: 06 May, 2020

Page: [93 - 109] Pages: 17

DOI: 10.2174/1570193X17999200507094857

Price: $65

Abstract

The heterocyclic compounds are the building blocks for the synthesis of the different biologically active compounds in the organic chemistry. Heterocyclic compounds have versatile synthetic applicability and biological activity. Pyrazole carboxylic acid derivatives are significant scaffold structures in heterocyclic compounds due to biologic activities such as antimicrobial, anticancer, inflammatory, antidepressant, antifungal anti-tubercular and antiviral, etc. The aim of this mini-review is an overview synthesis of pyrazole carboxylic acid derivatives and their biologic applications. The summarized literature survey presents biological activities of pyrazole carboxylic acid derivatives and their various synthetic methods in detail. This mini-review can be a guide to many scientists in medicinal chemistry.

Keywords: Antimicrobial activity, heterocyclic, bioactive properties, pharmacologic activity, pyrazole, synthesis.

Graphical Abstract


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