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Review Article

壳聚糖-纳米纤维素复合材料在再生医学中的应用

卷 27, 期 28, 2020

页: [4584 - 4592] 页: 9

弟呕挨: 10.2174/0929867327666200127152834

价格: $65

摘要

再生医学代表了一个新兴的多学科领域，将工程方法和生命科学的复杂性结合在一起，形成对微/纳米环境下结构-性能关系的统一的基本理解，以开发下一代支架和水凝胶来恢复或改善组织功能。壳聚糖具有一些独特的物理化学性质，使其成为多种应用领域的理想多糖，如生物医学、食品、保健品、农业、包装、涂料等。然而，壳聚糖在再生医学中的应用由于其机械性能、屏障性能和热性能的不足而受到限制。纤维素纳米材料因其优异的机械强度、易化学改性、生物相容性和与壳聚糖的良好相互作用，成为制备壳聚糖/壳聚糖支架和水凝胶的理想材料。壳聚糖/CNs生物纳米复合材料独特的力学和生物特性使其成为开发下一代再生医学应用生物支架和水凝胶的首选材料。本文综述了壳聚糖/CNs纳米复合材料的制备方法、力学性能、形态、细胞毒性/生物相容性等在再生医学中的应用，包括组织工程和创面敷料的应用。

关键词: 纤维素，纳米材料，形态，细胞毒性，生物医学应用，多糖。

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