Lessons from HIV Movement of Macromolecules Inside the Cell

Oliver   T.   Fackler; B.   Matija   Peterlin; Karsten      Weis

doi:10.2174/1566524013364167

Abstract

Molecular biological investigations of HIV have made fundamental contributions to our understanding of eukaryotic biology. These studies elucidated new paradigms in transcription, RNA and protein export from the nucleus to the cytoplasm, cellular activation, morphology and vesicular trafficking.

Keywords: HIV, Macromolecules, Response TAR RNA, Trans Activation, RNA polymerase II, TATA-box Binding, Transcription TBP-Associated Factor, TFIIA, Negative Elongation factor, Major histocompatibility

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Current Molecular Medicine

Title: Lessons from HIV Movement of Macromolecules Inside the Cell

Volume: 1 Issue: 1

Author(s): Oliver T. Fackler, B. Matija Peterlin and Karsten Weis

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Abstract: Molecular biological investigations of HIV have made fundamental contributions to our understanding of eukaryotic biology. These studies elucidated new paradigms in transcription, RNA and protein export from the nucleus to the cytoplasm, cellular activation, morphology and vesicular trafficking.

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Fackler T. Oliver, Peterlin Matija B. and Weis Karsten, Lessons from HIV Movement of Macromolecules Inside the Cell, Current Molecular Medicine 2001; 1 (1) . https://dx.doi.org/10.2174/1566524013364167