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General Review Article

耳念珠菌和医院感染

卷 21, 期 4, 2020

页: [365 - 373] 页: 9

弟呕挨: 10.2174/1389450120666190924155631

价格: $65

摘要

2009年发现了多药耐药（MDR）病原性真菌的存在。这种特殊的生物体能够在免疫力低下的人中引起医院内感染。该病原体与持续的念珠菌血症相关，死亡率高，并且对全球健康构成严重威胁。全基因组序列（WGS）调查发现了功能强大的系统化的假丝酵母基因型，这些基因型专门针对特定的地质区域，表明特定基因型在各省之间的传播。此外，这种生物经常表现出多药耐药性并显示出不同寻常的敏感性。商业化用于测试耳道假丝酵母的鉴定技术通常显示出不一致的结果，这种误鉴定会导致治疗失败，从而使念珠菌的管理变得复杂。迄今为止，已经从多个国家逐步记录到了假丝酵母，因此其预防控制措施对于中断其传播至关重要。在这篇综述中，我们讨论了流行性，生物学性，耐药性现象，毒力因子和耳假丝酵母感染的管理。

关键词: 耳念珠菌，新兴病原体，多药耐药性，念珠菌血症，医院感染。

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图形摘要

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