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Infectious Disorders - Drug Targets

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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

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Research Article

The Prevalence of Hepatitis C Virus Among Blood Donors Attending Samarra's General Hospital

Author(s): Abid Al-Mahmood* and Athraa Al-Jubori

Volume 20, Issue 5, 2020

Page: [693 - 697] Pages: 5

DOI: 10.2174/1871526519666190916101509

Price: $65

Abstract

Background: Hepatitis C is an infectious disease that affects primarily the liver; it is caused by hepatitis C virus (HCV). Cirrhosis and liver cancer are the common complications of the disease. So identifying prevalence and certain risk factors of the disease will promote preventive measures for the disease.

Aim and Objectives: By conducting this study, we will determine the prevalence of hepatitis C among blood donors who attended Samara General Hospital for donating blood.

Methods: A descriptive study was conducted on blood donors attending the hospital. The study was conducted during the period from February 2016 -November 2017. The sample included 850 persons. The demographic information, personal data and results of investigations were obtained according to a certain designed questionnaire. The subjects’ blood samples were tested to detect HCV antibodies by ELISA test.

Results: The prevalence of hepatitis C disease among blood donors in the current study according to HCV-Ab detection was 20/850 (2.4%) . The positive cases were more prevalent among males, married, those with previous blood transfusion, previous surgical procedures and those with an HIV positive spouse.

Conclusion: HCV infection is more prevalent in certain subjects with certain risk factors such as blood transfusion, surgical process, infected spouse.

Keywords: HCV, prevalence, blood donors, samarra, antibodies, hepatocellular carcinoma.

[1]
Houghton, M. hepatitis C viruses In:fields BN, Knipe DM, Howley PM, eds. Fields virology,3rd ed. Philadelphia,. Lippincott – Raven. , 1996; pp. 1035-1058.
[2]
Purcell, R.H. Hepatitis C virus.Encyclopedia of virology; Webster, R.G; Granoff, A., Ed.; Academic press Ltd: London, 1994, pp. 569-574.
[3]
Walsh, K.; Alexander, G.J. Update on chronic viral hepatitis. Postgrad. Med. J., 2001, 77(910), 498-505.
[http://dx.doi.org/10.1136/pmj.77.910.498] [PMID: 11470928]
[4]
Holmes-Mc Nary, M. Impact factors on develop-ment of cirrhosis and subsequent hepatocellular carcinoma.CompendContinEduc ent. 2001, 22, 19-33.
[5]
Alavian, S.M. Hepatitis C infection in Iran; A review article. Iran. J. Clin. Infect. Dis., 2009, 4, 47-59. [IJCID]
[6]
Forman, M.S.; Valsamakis, A. Hepatitis C virus. In: Murray’s Manual of Clinical Microbiology, 10th ed; Versalovic, J.; Carrol, K.C.; Funke, G.; Jorgensen, J.H.; Landry, M.L.; Warrock, D.W., Eds.; American Society of Microbiology: Press: Washington, 2011; pp. 1437-1455.
[7]
Viral hepatitis prevention board. Hepatitis A,B & C: defining workers at risk. Viral Hepatitis., 1995, 3
[8]
EPI/General directorate of preventive medicine /Iraqi MoH 1993.
[9]
Tarky, AM.; Akram, W.; Al-Naaimi, AS.; Omer, AR. Epidemiology of viral hepatitis B and C in Iraq: a national survey 2005-2006. Zanco. J Med. Sci, 2013, 17(1)
[10]
Hussein, N.R.; Haj Mohamad, S.; Almizori, L.A.; Taha, A.A. The Prevalence of Hepatitis B and C Viruses Among Blood Donors At-tending Blood Bank in Duhok, Kurdistan Region. Iraq International Journal of Infection, 2017, 4(1)e39008
[11]
Mohamoud, Y.A.; Riome, S.; Abu-Raddad, L.J. Epidemiology of hepatitis C virus in the Arabian Gulf countries: Systematic review and meta-analysis of prevalence. Int. J. Infect. Dis., 2016, 46, 116-125.
[http://dx.doi.org/10.1016/j.ijid.2016.03.012] [PMID: 26996460]
[12]
Mukhopadhyaya, A. Hepatitis C in India. J. Biosci., 2008, 33(4), 465-473.
[http://dx.doi.org/10.1007/s12038-008-0065-0] [PMID: 19208972]
[13]
Khodabandehloo, M.; Roshani, D.; Sayehmiri, K. Prevalence and trend of hepatitis C virus infection among blood donors in Iran: A systematic review and meta-analysis. J. Res. Med. Sci., 2013, 18(8), 674-682.
[PMID: 24379843]
[14]
Mohammed Abdullah, S. Prevalence of hepatitis B and C in donated blood from the jazan region of saudi arabia. Malays. J. Med. Sci., 2013, 20(2), 41-46.
[PMID: 23983576]
[15]
Madani, T.A. Hepatitis C virus infections reported in Saudi Arabia over 11 years of surveillance. Ann. Saudi Med., 2007, 27(3), 191-194.
[http://dx.doi.org/10.5144/0256-4947.2007.191] [PMID: 17568177]
[16]
El-Hazmi, M.M. Prevalence of HBV, HCV, HIV-1, 2 and HTLV-I/II infections among blood donors in a teaching hospital in the Central region of Saudi Arabia. Saudi Med. J., 2004, 25(1), 26-33.
[PMID: 14758374]
[17]
Bala, J.A.; Kawo, A.H.; Mukhtar, M.D.; Sarki, A.; Magaji, N.; Aliyu, I.A.; Sani, M.I. Prevalence of hepatitis C virus infection among blood donors in some selected hospitals in Kano, Nigeria. International Research Journal of Microbiology (IRJM) (ISSN: 2141-5463) Vol 3(6), pp 217-222. June 2012 Available online. http://www.interesjournals.org/IRJM
[18]
Qureshi, H; Bile, KM; Jooma, R; Alam, SE Afridi, HU Prevalence of hepatitis B and C viral infections in Pakistan: findings of a national survey appealing for effective prevention and control measures Eastern Mediterranean health journal = La revue de sante dela Mediterranee orientale = al-Majallah al-sihhiyah li-sharq almutawassit, 2010, 16(Suppl), S15-S23.
[19]
El-Zanaty, F.; Way, A. Egypt Demographic and Health Survey 2008. Egyptian: Ministry of Health; El-Zanaty and Associates, and Macro International: Cairo, 2009.
[20]
Alter, M.J. Epidemiology of hepatitis C virus infection. World J. Gastroenterol., 2007, 13(17), 2436-2441.
[http://dx.doi.org/10.3748/wjg.v13.i17.2436] [PMID: 17552026]
[21]
Gomaa, A.; Allam, N.; Elsharkawy, A.; El-kassas, M. Hepatits C infection on Egypt: prevalence, impact and management strategies. Hepat. Medicine: Evidence and Research, 2017, 9, 17-25.
[22]
Fakeeh, M.; Zaki, A.M.; Hepatitis, C. Hepatitis C: prevalence and common genotypes among ethnic groups in Jeddah, Saudi Arabia. Am. J. Trop. Med. Hyg., 1999, 61(6), 889-892.
[http://dx.doi.org/10.4269/ajtmh.1999.61.889] [PMID: 10674665]
[23]
Alter, M.J.; Kruszon-Moran, D.; Nainan, O.V.; McQuillan, G.M.; Gao, F.; Moyer, L.A.; Kaslow, R.A.; Margolis, H.S. The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. N. Engl. J. Med., 1999, 341(8), 556-562.
[http://dx.doi.org/10.1056/NEJM199908193410802] [PMID: 10451460]
[24]
Armstrong, G.L.; Wasley, A.; Simard, E.P.; McQuillan, G.M.; Kuhnert, W.L.; Alter, M.J. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann. Intern. Med., 2006, 144(10), 705-714.
[http://dx.doi.org/10.7326/0003-4819-144-10-200605160-00004] [PMID: 16702586]
[25]
Law, M.G.; Dore, G.J.; Bath, N.; Thompson, S.; Crofts, N.; Dolan, K.; Giles, W.; Gow, P.; Kaldor, J.; Loveday, S.; Powell, E.; Spencer, J.; Wodak, A. Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001. Int. J. Epidemiol., 2003, 32(5), 717-724.
[http://dx.doi.org/10.1093/ije/dyg101] [PMID: 14559738]
[26]
Shepard, C.W.; Finelli, L.; Alter, M.J. Global epidemiology of hepatitis C virus infection. Lancet Infect. Dis., 2005, 5(9), 558-567.
[http://dx.doi.org/10.1016/S1473-3099(05)70216-4] [PMID: 16122679]
[27]
Hassanshahi, G.; Arababadi, M.K.; Assar, S.; Hakimi, H.; Karimabad, M.N.; Abedinzadeh, M.; Rafatpanah, H.; Derakhshan, R. Post-transfusion-transmitted hepatitis C virus infection: a study on thalassemia and hemodialysis patients in southeastern Iran. Arch. Virol., 2011, 156(7), 1111-1115.
[http://dx.doi.org/10.1007/s00705-011-0950-y] [PMID: 21340738]
[28]
Goh, K.T.; Doraisingham, S.; Tan, K.L.; Oon, C.J.; Ho, M.L.; Chen, A.J.; Chan, S.H. The hepatitis B immunization programme in Singapore. Bull. World Health Organ., 1989, 67(1), 65-70.
[PMID: 2523251]
[29]
Haidar, N.A. Prevalence of hepatitis B and hepatitis C in blood donors and high risk groups in Hajjah, Yemen Republic. Saudi Med. J., 2002, 23(9), 1090-1094.
[PMID: 12370719]
[30]
Sallam, T.A.; Tong, C.Y.W.; Cuevas, L.E.; Raja’a, Y.A.; Othman, A.M.; Al-Kharsa, K.R. Prevalence of blood-borne viral hepatitis in different communities in Yemen. Epidemiol. Infect., 2003, 131(1), 771-775.
[http://dx.doi.org/10.1017/S0950268803008653] [PMID: 12948378]
[31]
Alnaqdy, A.; Alfahdi, A.; Alkobaisi, M.; Kaminski, G.Z. Prevalence of autoantibodies in patients with hepatitis C virus infection in Oman. Ann. Saudi Med., 2003, 23(3-4), 127-131.
[http://dx.doi.org/10.5144/0256-4947.2003.127] [PMID: 16985299]
[32]
Magder, L.S.; Fix, A.D.; Mikhail, N.N.; Mohamed, M.K.; Abdel-Hamid, M.; Abdel-Aziz, F.; Medhat, A.; Strickland, G.T. Estimation of the risk of transmission of hepatitis C between spouses in Egypt based on seroprevalence data. Int. J. Epidemiol., 2005, 34(1), 160-165.
[http://dx.doi.org/10.1093/ije/dyh370] [PMID: 15647312]

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