Abstract
Background: Standardization of herbal formulation is mandatory for the quality check of drugs for assurance of their therapeutic value. According to the World Health Organization reports, about 80% of the world’s population relies on traditional medicine. Dhatryadi Ghrita, a polyherbal preparation containing eleven ingredients, has a sweet taste, cold potency and sweet post-digestive effects.
Objective: In this research article, quality control for ghrita has been assessed for some of the ingredients of Dhatryadi Ghrita.
Materials & Methods: Quality control assessment was done with the aid of the HPTLC method. Precoated silica gel GF 254 was used as the stationary phase and the developed method used benzene:ethyl alcohol (9:1v/v). Scanning and quantification of the plates were performed at 254 nm and 366 nm.
Result: The study confirms the presence of different constituents of Ghrita.
Conclusion: The routine analysis of Ghrita was facilitated with simple, accurate and cost-effective HPTLC method. Data has been provided to demonstrate the present and future applicability of the methods of quality control assessment of Dhatryadi Ghrita.
Keywords: Quality control, Dhatryadi Ghrita, HPTLC, Traditional medicine, Emblica officinalis, herbal formulations.
Graphical Abstract
[http://dx.doi.org/10.2174/1874220301805010047]
[http://dx.doi.org/10.7897/2277-4343.082111]
[http://dx.doi.org/10.7897/2277-4343.066128]
[http://dx.doi.org/10.4103/0253-7613.135946] [PMID: 25097272]
[http://dx.doi.org/10.1186/1749-8546-3-7] [PMID: 18588699]
[http://dx.doi.org/10.7897/2277-4343.07136]
[http://dx.doi.org/10.7897/2277-4343.05382]
[http://dx.doi.org/10.7897/2277-4343.07133]
[http://dx.doi.org/10.1177/009286150003400102]
[http://dx.doi.org/10.1016/j.jfca.2008.02.008]
[http://dx.doi.org/10.1007/978-3-642-88488-7_3]
[http://dx.doi.org/10.1002/jssc.201000696] [PMID: 21268251]
[http://dx.doi.org/10.1016/j.jtcme.2016.05.006] [PMID: 8417092]
[http://dx.doi.org/10.1155/2013/627375] [PMID: 23634172]
[http://dx.doi.org/10.18203/2320-1770.ijrcog20174044]
[http://dx.doi.org/10.4103/0974-8520.82033] [PMID: 22048534]