Search Result "thymidine kinase (TK) by-pass"


CycloSal-dRFIB, a Thymidine Mimetic, Thymidine Kinase by-Pass Nucleoside Prodrug: Radioiodination, in vitro Cellular Uptake and Biodistribution in Murine Models

Journal: Current Radiopharmaceuticals
Volume: 3 Issue: 4 Year: 2010 Page: 267-274
Author(s): Anke Stahlschmidt, William Sun, Aihua Zhou, Hans- Jurgen Machulla, Edward E. Knaus, Leonard I. Wiebe

Influence of the Bystander Effect on HSV-tk / GCV Gene Therapy. A Review.

Journal: Current Gene Therapy
Volume: 2 Issue: 3 Year: 2002 Page: 307-322
Author(s): Ingrid J. van Dillen, Nanno H. Mulder, Willem Vaalburg, Erik F.J. de Vries, Geke A.P. Hospers

Radiolabeled Nucleoside Analogues for PET Imaging of HSV1-tk Gene Expression

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1617-1632
Author(s): Mian M. Alauddin, Juri G. Gelovani

Radiosynthesis of 2-deoxy-2-[18F]fluorothymidine ([18F]FT), a Putative PET Agent for Imaging HSV-TK Expression

Journal: Current Radiopharmaceuticals
Volume: 2 Issue: 1 Year: 2009 Page: 75-82
Author(s): William Sun, John Wilson, Piyush Kumar, Edward Knaus, Leonard Wiebe

N3-Substituted Thymidine Analogues: Radiosyntheses of N3-[4-(4-(2-[18F] fluoroethyl)phenyl)butyl]thymidine and N3-[5-(4-(2-[18F]fluoroethyl)- phenyl)pentyl]thymidine for PET

Journal: Current Radiopharmaceuticals
Volume: 2 Issue: 1 Year: 2009 Page: 2-8
Author(s): Pradip Ghosh, Juri G. Gelovani, Mian M. Alauddin

Thymidine Phosphorylase and Fluoropyrimidines Efficacy: A Jekyl and Hyde Story

Journal: Current Medicinal Chemistry - Anti-Cancer Agents
Volume: 4 Issue: 2 Year: 2004 Page: 71-81
Author(s): Joseph Ciccolini, Alexandre Evrard, Pierre Cuq

Research Article

Enzyme-Driven Chemo-and Radiation-Therapy with 12 Pyrimidine Nucleoside Analogs Not Yet in the Clinic

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2017 Page: 250-264
Author(s): Sheldon Greer,Tieran Han,Cristina Dieguez,Nicola McLean,Rafael Saer,Isildinha Reis,Joe Levi,Victor E. Marquez

Gene Therapy: The First Approved Gene-Based Medicines, Molecular Mechanisms and Clinical Indications

Journal: Current Molecular Pharmacology
Volume: 1 Issue: 1 Year: 2008 Page: 13-23
Author(s): J. K. Raty, J. T. Pikkarainen, T. Wirth, S. Yla-Herttuala

Synthetic Src-Kinase Domain Inhibitors and Their Structural Requirements

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 660-680
Author(s): Silvia Schenone, Fabrizio Manetti, Maurizio Botta

Research Article

Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV)

Journal: Medicinal Chemistry
Volume: 13 Issue: 5 Year: 2017 Page: 453-464
Author(s): Yi-ning Wen,Zhi-feng Zhang,Ning-Ning Liu,Graciela Andrei,Robert Snoeck,Yu-Hong Xiang,Dominique Schols,Xue Chen,Zhuo-Yong Zhang,Qing-Shan Zhang,Qin-Pei Wu

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