Search Result "subsites of active site"


Mapping of the Active Site of Proteases in the 1960s and Rational Design of Inhibitors/Drugs in the 1990s

Journal: Current Protein & Peptide Science
Volume: 6 Issue: 6 Year: 2005 Page: 501-512
Author(s): I. Schechter

Structural Elements of Ligand Recognition Site in Secretory Phospholipase A2 and Structure-Based Design of Specific Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 8 Year: 2007 Page: 757-764
Author(s): Nagendra Singh, Rishi K. Somvanshi, Sujata Sharma, Sharmistha Dey, Punit Kaur, Tej P. Singh

Interaction of EGLIN C Variants with the Extended Subsites of the Precursor Processing Proteases*.

Journal: Protein & Peptide Letters
Volume: 12 Issue: 5 Year: 2005 Page: 415-420
Author(s): Tomoko Komiyama

Probing Proteinase Active Sites Using Oriented Peptide Mixture Libraries - ADAM-10

Journal: Letters in Drug Design & Discovery
Volume: 1 Issue: 1 Year: 2004 Page: 6-13
Author(s): John L. Krstenansky, Jihong Wang, Gregg R. Chenail, Matthew R. Tiffany, Geoffrey M. Kuesters, Barbara C. Natke, John J. Nestor, Jr.

Research Article

Computational Analysis of Physicochemical Factors Driving CYP2D6 Ligand Interaction

Journal: Current Computer-Aided Drug Design
Volume: 13 Issue: 1 Year: 2017 Page: 39-47
Author(s): Olujide O. Olubiyi, Maryam O. Olagunju, Abiola O. Obisesan

Regulation of Xanthine Oxidase Activity by Substrates at Active Sites via Cooperative Interactions between Catalytic Subunits: Implication to Drug Pharmacokinetics

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 69-78
Author(s): L. A. Tai, K. C. Hwang

Unraveling Sub-Site Specificities of Peptidic Serine Protease Inhibitors by Substitutional and Structural Analysis

Journal: Protein & Peptide Letters
Volume: 12 Issue: 5 Year: 2005 Page: 449-456
Author(s): Wolfgang Hohne, Kai Hilpert

Seeking the Active Site of the AT1 Receptor for Computational Docking Studies

Journal: Drug Design Reviews - Online (Discontinued)
Volume: 2 Issue: 7 Year: 2005 Page: 537-545
Author(s): P. Zoumpoulakis, T. Mavromoustakos

Review Article

Structural Understanding of SARS-CoV-2 Drug Targets, Active Site ContourMap Analysis and COVID-19 Therapeutics

Journal: Current Molecular Pharmacology
Volume: 15 Issue: 2 Year: 2022 Page: 418-433
Author(s): Chandrabose Selvaraj,Dhurvas Chandrasekaran Dinesh,Petra Krafcikova,Evzen Boura,Murali Aarthy,Muthuraja Arun Pravin,Sanjeev Kumar Singh

The Peripheral Anionic Site of Acetylcholinesterase: Structure, Functions and Potential Role in Rational Drug Design

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 2 Year: 2006 Page: 217-225
Author(s): G. Johnson, S. W. Moore

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