Search Result "scPTZ ED50"


In Silico Validation and Structure Activity Relationship Study of a Series of Pyridine-3-carbohydrazide Derivatives as Potential Anticonvulsants in Generalized and Partial Seizures

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 13 Issue: 2 Year: 2013 Page: 132-140
Author(s): Reema Sinha,Udai Vir Singh Sara,Ratan Lal Khosa,James Stables,Jainendra Jain

Synthesis and Screening of Substituted Thiosemicarbazone Derivatives: An Approach towards Novel Anticonvulsant Search

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 60-65
Author(s): Priyanka Singh, Jainendra Jain, Reema Sinha, Abdul Samad, Rajeev Kumar, Manav Malhotra

Research Article

Synthesis and Anticonvulsant Activity of 3-(alkylamino, alkoxy)-1,3,4,5- Tetrahydro-2H-benzo [b] azepine-2-one Derivatives

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 17 Issue: 6 Year: 2018 Page: 448-457
Author(s): Xia Huang,Tie Chen,Rong-Bi Han,Feng-Yu Piao

Research Article open access plus

Synthesis and Evaluation of Anticonvulsant Activities of 4-Phenylpiperidin- 2-one Derivatives

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 6 Year: 2020 Page: 713-724
Author(s): Shi-Ben Wang,Hui Liu,Guang-Yong Li,Kang Lei,Xiao-Jing Li,Zhe-Shan Quan,Xue-Kun Wang

Research Article

Synthesis and Evaluation of N-substituted (Z)-5-(Benzo[d][1,3]dioxol-5- ylmethylene)-2-Thioxothiazolidin-4-one Derivatives and 5-Substituted- Thioxothiazolidindione Derivatives as Potent Anticonvulsant Agents

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 18 Issue: 10 Year: 2019 Page: 798-807
Author(s): Shiyang Dong,Yanhua Liu,Jun Xu,Yue Hu,Limin Huang,Zengtao Wang

Research Article

Design, Synthesis and Evaluation of the Antidepressant and Anticonvulsant Activities of Triazole-Containing Benzo[d]oxazoles

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 16 Issue: 2 Year: 2017 Page: 187-198
Author(s): Ming-Xia Song,Bao-Qi Rao,Bin-Bin Cheng,Wu Yi,Hong Zeng,You-gen Luo,Xian-Qing Deng

Research Article

Evaluation of Anticonvulsant Activity and Toxicity Screening of Semicarbazones Derived from Quinazolinone Scaffold

Journal: Current Bioactive Compounds
Volume: 15 Issue: 5 Year: 2019 Page: 573-581
Author(s): Meena K. Yadav,Laxmi Tripathi,Diptendu Goswami

Research Article

Synthesis of Novel 8-alkylamino-5, 6-dihydro-4H-benzo[f] [1,2,4]triazolo [4,3-a]azepines as Anticonvulsant Agents

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15 Issue: 10 Year: 2016 Page: 1333-1343
Author(s): Hui-Fan Wu,Rong-Bi Han,Chun-Zi Jin,Feng-Yu Piao

Research Article

Design, Synthesis, Anticonvulsant Activity, Preclinical Study and Pharmacokinetic Performance of N-{[3-(4-chlorophenyl)-4-oxo-3, 4-dihydroquinazolin- 2-yl] methyl}, 2-[(2-isopropyl-5-methyl) 1-cyclo Hexylidene] Hydrazinecarboxamide

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 31-45
Author(s): Meena K. Yadav,Laxmi Tripathi

Research Article

Rationale Design, Synthesis, and Pharmacological Evaluation of Isatin Analogues as Antiseizure Agents

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 12 Year: 2021 Page: 1146-1164
Author(s): Sandip Firke,Rameshwar Cheke,Vinod Ugale,Saurabh Khadse,Manish Gagarani,Sanjay Bari,Sanjay Surana

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