Search Result "rules of thumb lead optimization"


Multi-Parameter Optimization: Identifying High Quality Compounds with a Balance of Properties

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1292-1310
Author(s): Matthew D. Segall

Methodologies to Assess Brain Drug Delivery in Lead Optimization

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2009 Page: 148-162
Author(s): Margareta Hammarlund-Udenaes, Ulf Bredberg, Markus Friden

In-Silico ADME Models: A General Assessment of their Utility in Drug Discovery Applications

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 358-381
Author(s): M. Paul Gleeson, Anne Hersey, Supa Hannongbua

An Optimized System for Sentiment Analysis using Twitter Data

Ebook: Challenges and Opportunities for Deep Learning Applications in Industry 4.0
Volume: 1 Year: 2022
Author(s):
Doi: 10.2174/9789815036060122010010

From Drug Target to Leads-Sketching A Physicochemical Pathway for Lead Molecule Design In Silico

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 3 Year: 2007 Page: 3454-3470
Author(s): S. A. Shaikh, T. Jain, G. Sandhu, N. Latha, B. Jayaram

open access plus

Optimizing the Structure of Tetracyanoplatinate (II): A Comparison of Relativistic Density Functional Theory Methods

Journal: Current Inorganic Chemistry (Discontinued)
Volume: 3 Issue: 3 Year: 2013 Page: 213-219
Author(s): Asmus O. Dohn,Klaus B. Moller,Stephan P. A. Sauer

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1600-1629
Author(s): Jeffrey S. Albert, Niklas Blomberg, Alexander L. Breeze, Alastair J. H. Brown, Jeremy N. Burrows, Philip D. Edwards, Rutger H. A. Folmer, Stefan Geschwindner, Ed J. Griffen, Peter W. Kenny, Thorsten Nowak, Lise-Lotte Olsson, Hitesh Sanganee, Adam B. Shapiro

Feature Selection and Classification Employing Hybrid Ant Colony Optimization/Random Forest Methodology

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 5 Year: 2009 Page: 507-513
Author(s): Diwakar Patil, Rahul Raj, Prashant Shingade, Bhaskar Kulkarni, Valadi K. Jayaraman

Review Article

The Structure-property Relationships of GPCR-targeted DrugsApproved between 2011 and 2021

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 31 Year: 2023 Page: 3527-3549
Author(s):

Anti Cancer Activity on Graviola, an Exciting Medicinal Plant Extract vs Various Cancer Cell Lines and a Detailed Computational Study on its Potent Anti-Cancerous Leads

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 1666-1673
Author(s): Jeno Paul, R. Gnanam, R. M. Jayadeepa, L. Arul

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