Search Result "reductoisomerase"


Targeting the Methyl Erythritol Phosphate (MEP) Pathway for Novel Antimalarial, Antibacterial and Herbicidal Drug Discovery: Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (DXR) Enzyme

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 1 Year: 2007 Page: 1161-1177
Author(s): Nidhi Singh, Gweneal Cheve, Mitchell A. Avery, Christopher R. McCurdy

Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2012 Page: 706-728
Author(s): Emily R. Jackson,Cynthia S. Dowd

Isoprenoid Biosynthesis of the Apicoplast as Drug Target

Journal: Current Drug Targets
Volume: 8 Issue: 1 Year: 2007 Page: 3-13
Author(s): Jochen Wiesner, Hassan Jomaa

The Malarial Drug Target Plasmodium falciparum 1-Deoxy-D-Xylulose-5- Phosphate Reductoisomerase (PfDXR): Development of a 3-D Model for Identification of Novel, Structural and Functional Features and for Inhibitor Screening (Supplementary Information)

Journal: Protein & Peptide Letters
Volume: 17 Issue: 1 Year: 2010 Page: 109-120
Author(s): Jessica L. Goble, Matthew R. Adendorff, Tjaart A.P. de Beer, Linda L. Stephens, Gregory L. Blatch

Recent Advances in Antimalarial Compounds and their Patents

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 7 Year: 2007 Page: 759-773
Author(s): Alka Mital

Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis. Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes

Journal: Current Enzyme Inhibition
Volume: 7 Issue: 2 Year: 2011 Page: 79-95
Author(s): Jerome de Ruyck, Johan Wouters, C. Dale Poulter

Transition-State-Guided Drug Design for Treatment of Parasitic Neglected Tropical Diseases

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 15 Year: 2014 Page: 1781-1793
Author(s): A.S. Murkin,M.M. Moynihan

The Druggable Antimalarial Target PfDXR: Overproduction Strategies and Kinetic Characterization

Journal: Protein & Peptide Letters
Volume: 20 Issue: 2 Year: 2013 Page: 115-124
Author(s): Jessica L. Goble,Hailey Johnson,Jaco de Ridder,Linda L. Stephens,Abraham Louw,Gregory L. Blatch,Aileen Boshoff

Target Validation for Drug Discovery in Parasitic Organisms

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 5 Year: 2002 Page: 425-438
Author(s): Laurie K. Jackson, Margaret A. Phillips

The Methylerythritol Phosphate (MEP) Pathway for Isoprenoid Biosynthesis as a Target for the Development of New Drugs Against Tuberculosis

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 9 Year: 2011 Page: 1325-1338
Author(s): C. Obiol-Pardo, J. Rubio-Martinez, S. Imperial

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