Search Result "recombinant CYP3A4 isozyme"


Characterization of CYP3A Isozymes Involved in the Metabolism of Domperidone: Role of Cytochrome b5 and Inhibition by Ketoconazole

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 95-103
Author(s): Veronique Michaud, Chantale Simard, Jacques Turgeon

In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities

Journal: Drug Metabolism Letters
Volume: 9 Issue: 1 Year: 2015 Page: 48-62
Author(s): Charles Awortwe,Vamshi K. Manda,Cristina Avonto,Shabana I. Khan,Ikhlas A. Khan,Larry A. Walker,Patrick J. Bouic,Bernd Rosenkranz

Co-Expression of Recombinant Human CYP2C9 with Human Cytochrome P450 Reductase in Protease Deficient S. cerevisiae Strain at a Higher Scale Yields an Enzyme of Higher Specific Activity

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 246-253
Author(s): K. N. Purnachandra Rao, Sunil Kumar Suman, Y. Ravi Kiran, Arup Ranjan Kuanr, Anuj Kumar Gupta, Kunal Bhalla, Vipul Kumar, Prabuddha Kundu, Kajal Arora, Rajeev Soni

Utility of Nicotiana tabacum Cell Suspension Cultures Expressing Human CYP1A1, CYP1A2 and CYP3A4 to Study the Oxidative Metabolism of the Herbicide 14C-Fluometuron

Journal: Drug Metabolism Letters
Volume: 3 Issue: 1 Year: 2009 Page: 18-27
Author(s): Maren Anne Breuer, Burkhard Schmidt, Ingolf Schuphan

Macaque CYP2C76 Encodes Cytochrome P450 Enzyme Not Orthologous to Any Human Isozymes

Journal: Current Drug Metabolism
Volume: 11 Issue: 2 Year: 2010 Page: 142-152
Author(s): Yasuhiro Uno, Hideki Fujino, Kazuhide Iwasaki, Masahiro Utoh

Pharmacokinetic Changes of Drugs in Rat Model of Acute Renal Failure Induced by Uranyl Nitrate: Correlation Between Drug Metabolism and Hepatic Microsomal Cytochrome P450 Isozymes

Journal: Current Clinical Pharmacology
Volume: 1 Issue: 2 Year: 2006 Page: 193-205
Author(s): Myung G. Lee, Joo H. Lee, Jung M. Oh

Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation

Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 144-150
Author(s): Julius L. Apuy, Cathie Xiang, Sarah Franc, Sayee G. Hegde, Robert Hubbard, Jingjing Zhao, Mehran F. Moghaddam

Identifying a Higher Throughput Assay for Metabolism Dependent Inhibition (MDI)

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 104-113
Author(s): Mahmud Kajbaf, Emiliano Palmieri, Raffaele Longhi, Stefano Fontana

Metabolism of Loratadine and Further Characterization of Its In Vitro Metabolites

Journal: Drug Metabolism Letters
Volume: 3 Issue: 3 Year: 2009 Page: 162-170
Author(s): Anima Ghosal, Samir Gupta, Ragu Ramanathan, Yuan Yuan, Xiaowen Lu, Ai Duen (Iris) Su, Narciso Alvarez, Shmuel Zbaida, Swapan K. Chowdhury, Kevin B. Alton

Evaluation of Different Approaches to Identifying a Higher Throughput Assay for Time-Dependent Inhibition (TDI)

Journal: Drug Metabolism Letters
Volume: 5 Issue: 2 Year: 2011 Page: 104-113
Author(s): M. Kajbaf, R. Longhi, S. Fontana

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