Search Result "reactive electro-philic metabolites"


Extrahepatic Targets and Cellular Reactivity of Drug Metabolites

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 408-437
Author(s): Hilmi Orhan

Research Article

Role of Oxidative Stress and Reactive Metabolites in Cytotoxicity & Mitotoxicity of Clozapine, Diclofenac and Nifedipine in CHO-K1 Cells In Vitro

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 23 Issue: 14 Year: 2023 Page: 1725-1739
Author(s):

Role of Cyclic Tertiary Amine Bioactivation to Reactive Iminium Species: Structure Toxicity Relationship

Journal: Current Drug Metabolism
Volume: 12 Issue: 1 Year: 2011 Page: 35-50
Author(s): Lucija Peterlin Masic

Research Article

Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study

Journal: Drug Metabolism Letters
Volume: 13 Issue: 1 Year: 2019 Page: 64-76
Author(s): Muthusamy Ramesh,Prasad V. Bharatam

Many Drugs and Phytochemicals Can Be Activated to Biological Reactive Intermediates

Journal: Current Drug Metabolism
Volume: 9 Issue: 4 Year: 2008 Page: 344-351
Author(s): William W. Johnson

open access plus

Linking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 15 Year: 2016 Page: 1705-1716
Author(s): Eric P. Trautman,Jason M. Crawford

Metabolomics in Drug Intolerance

Journal: Current Drug Metabolism
Volume: 10 Issue: 9 Year: 2009 Page: 947-955
Author(s): Inmaculada Andreu, Cristobalina Mayorga, Miguel A. Miranda

Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Chemical Mechanisms, Structure-Activity Relationships and Relationship to Clinical Drug-Drug Interactions and Idiosyncratic Adverse Drug Reactions

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 407-447
Author(s): Amit S. Kalgutkar, R. Scott Obach, Tristan S. Maurer

Exploiting Endogenous Cellular Process to Generate Quinone Methides In Vivo

Journal: Current Organic Chemistry
Volume: 18 Issue: 1 Year: 2014 Page: 70-85
Author(s): Sheng Cao,Xiaohua Peng

Free Radicals and Antioxidants: How to Reestablish Redox Homeostasis in Chronic Diseases?

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 2 Year: 2013 Page: 3397-3415
Author(s): V. Bocci, G. Valacchi

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