Search Result "presenilin 1 (PS1)"


The Catalytic Core of γ-Secretase: Presenilin Revisited

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 147-157
Author(s): Harald Steiner

Evidence that Enzyme Processivity Mediates Differential Aβ Production by PS1 and PS2

Journal: Current Alzheimer Research
Volume: 10 Issue: 1 Year: 2013 Page: 4-10
Author(s): Sean A. Pintchovski,Dale B. Schenk,Guriqbal S. Basi

Physiological Functions of Presenilins; Beyond γ-Secretase

Journal: Current Pharmaceutical Biotechnology
Volume: 15 Issue: 1 Year: 2014 Page: 1019-1025
Author(s): Ibolya Stiller, Beata Lizak, Gabor Banhegyi

Recent Insights on the Pro-Apoptotic Phenotype Elicited by Presenilin 2 and its Caspase and Presenilinase-Derived Fragments

Journal: Current Alzheimer Research
Volume: 2 Issue: 5 Year: 2005 Page: 507-514
Author(s): Cristine A da Costa

Familial Alzheimers Disease Mutations in Presenilin 1 Do Not Alter Levels of the Secreted Amyloid-β Protein Precursor Generated by β-Secretase Cleavage

Journal: Current Alzheimer Research
Volume: 7 Issue: 1 Year: 2010 Page: 21-26
Author(s): C. Zhang, A. Browne, D. Y. Kim, R. E. Tanzi

Synaptic Fatigue is More Pronounced in the APP/PS1 Transgenic Mouse Model of Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 2 Issue: 2 Year: 2005 Page: 137-140
Author(s): Hong Zhang, Bing Gong, Shumin Liu, Mauro Fa, Ipe Ninan, Agnieszka Staniszewski, Ottavio Arancio

Presenilin and γ -Secretase Activity: A Viable Therapeutic Target for Alzheimers Disease?

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 2 Year: 2010 Page: 128-140
Author(s): Run Yan, Justin V. McCarthy

Changes in the Expression of the Alzheimers Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction

Journal: Current Alzheimer Research
Volume: 8 Issue: 3 Year: 2011 Page: 313-322
Author(s): A. Li, C. Zhou, J. Moore, P. Zhang, T.-H. Tsai, H.-C. Lee, D. M. Romano, M. L.McKee, D. A. Schoenfeld, M. J. Serra, K. Raygor, H. F. Cantiello, J. G. Fujimoto, R. E. Tanzi

From Presenilinase to γ-Secretase, Cleave to Capacitate

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 172-178
Author(s): Weiming Xia

Protein Trafficking and Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 1 Issue: 1 Year: 2004 Page: 1-10
Author(s): Kengo Uemura, Akira Kuzuya, Shun Shimohama

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