Search Result "pleckstrin-homology (PH) domain"


Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2727-2742
Author(s): E. J. Meuillet

Recent Development of Anticancer Therapeutics Targeting Akt

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 6 Issue: 1 Year: 2011 Page: 146-159
Author(s): John K. Morrow, Lei Du-Cuny, Lu Chen, Emmanuelle J. Meuillet, Eugene A. Mash, Garth Powis, Shuxing Zhang

A Directly Labeled TR-FRET Assay for Monitoring Phosphoinositide-3-Kinase Activity

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 7 Year: 2006 Page: 565-570
Author(s): Xiaoke Yang, Puyao Li, Larry Feldberg, Steven C. Kim, Michael Bowman, Irwin Hollander, Robert Mallon, Stanley F. Wolf

Recent Progress in the Development of ATP-Competitive and Allosteric Akt Kinase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1349-1363
Author(s): Lindsley W. Craig, Barnett F. Stanley, Yaroschak Melissa, Bilodeau T. Mark, Layton E. Mark

The Akt/PKB Family of Protein Kinases: A Review of Small Molecule Inhibitors and Progress Towards Target Validation

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 2 Year: 2005 Page: 109-125
Author(s): Stanley F. Barnett, Mark T. Bilodeau, Craig W. Lindsley

PDZ Domain-mediated Protein Interactions: Therapeutic Targets in Neurological Disorders

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 23 Year: 2014 Page: 2632-2641
Author(s): Z. Khan,M. Lafon

RhoGEFs in Cell Motility: Novel Links Between Rgnef and Focal Adhesion Kinase

Journal: Current Molecular Medicine
Volume: 14 Issue: 2 Year: 2014 Page: 221-234
Author(s): N.L.G. Miller,E.G. Kleinschmidt,D.D. Schlaepfer

Probing the Phosphopeptide Specificities of Protein Tyrosine Phosphatases, SH2 and PTB Domains with Combinatorial Library Methods

Journal: Current Protein & Peptide Science
Volume: 3 Issue: 4 Year: 2002 Page: 365-397
Author(s): Stefan W. Vetter, Zhong-Yin Zhang

Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases

Journal: Current Drug Targets
Volume: 9 Issue: 8 Year: 2008 Page: 626-640
Author(s): Fumio Sakane, Shin-ichi Imai, Masahiro Kai, Satoshi Yasuda, Hideo Kanoh

Review Article

Protein Interaction Domains: Structural Features and Drug Discovery Applications (Part 2)

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 5 Year: 2021 Page: 854-892
Author(s): Marian Vincenzi,Flavia Anna Mercurio,Marilisa Leone

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