Search Result "pleckstrin-homology"


Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2727-2742
Author(s): E. J. Meuillet

Recent Development of Anticancer Therapeutics Targeting Akt

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 6 Issue: 1 Year: 2011 Page: 146-159
Author(s): John K. Morrow, Lei Du-Cuny, Lu Chen, Emmanuelle J. Meuillet, Eugene A. Mash, Garth Powis, Shuxing Zhang

The Akt/PKB Family of Protein Kinases: A Review of Small Molecule Inhibitors and Progress Towards Target Validation

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 2 Year: 2005 Page: 109-125
Author(s): Stanley F. Barnett, Mark T. Bilodeau, Craig W. Lindsley

Recent Progress in the Development of ATP-Competitive and Allosteric Akt Kinase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1349-1363
Author(s): Lindsley W. Craig, Barnett F. Stanley, Yaroschak Melissa, Bilodeau T. Mark, Layton E. Mark

A Directly Labeled TR-FRET Assay for Monitoring Phosphoinositide-3-Kinase Activity

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 7 Year: 2006 Page: 565-570
Author(s): Xiaoke Yang, Puyao Li, Larry Feldberg, Steven C. Kim, Michael Bowman, Irwin Hollander, Robert Mallon, Stanley F. Wolf

RhoGEFs in Cell Motility: Novel Links Between Rgnef and Focal Adhesion Kinase

Journal: Current Molecular Medicine
Volume: 14 Issue: 2 Year: 2014 Page: 221-234
Author(s): N.L.G. Miller,E.G. Kleinschmidt,D.D. Schlaepfer

Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases

Journal: Current Drug Targets
Volume: 9 Issue: 8 Year: 2008 Page: 626-640
Author(s): Fumio Sakane, Shin-ichi Imai, Masahiro Kai, Satoshi Yasuda, Hideo Kanoh

Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1923-1945
Author(s): Giuliana Cassinelli, Valentina Zuco, Laura Gatti, Cinzia Lanzi, Nadia Zaffaroni, Diego Colombo, Paola Perego

Research Article

In Silico Docking of Vitamin E Isomers on Transport Proteins

Journal: Current Computer-Aided Drug Design
Volume: 16 Issue: 4 Year: 2020 Page: 467-472
Author(s): Nurul Syeefa Zulkiflee,Siti Amilia Awang,Woo Xian Ming,Muhammad Fauzan Wira’i Kamilan,M Yuveneshwari Mariappan,Tan Jen Kit

Research Article

PHD-BAH Domain in ASH1L Could Recognize H3K4 Methylation and Regulate the Malignant Behavior of Cholangiocarcinoma

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 24 Issue: 17 Year: 2024 Page: 1264-1274
Author(s):

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