Search Result "mutant polyQ proteins"


New Targets for Therapy in Polyglutamine (polyQ) Expansion Diseases

Journal: Current Drug Therapy
Volume: 3 Issue: 3 Year: 2008 Page: 177-189
Author(s): Lorena Perrone, Mariarosa A.B. Melone

Therapeutic Approaches to Polyglutamine Diseases: Combating Protein Misfolding and Aggregation

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 2 Year: 2006 Page: 2543-2555
Author(s): Martin Herbst, Erich E. Wanker

Towards the Treatment of Polyglutamine Diseases: The Modulatory Role of Protein Context

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2010 Page: 3058-3068
Author(s): A. L. Robertson, S. P. Bottomley

Transcriptional Dysregulation: A Therapeutic Target for Polyglutamine Diseases

Journal: Current Medicinal Chemistry - Central Nervous System Agents
Volume: 5 Issue: 2 Year: 2005 Page: 119-127
Author(s): Jonathan Cornett, Meyer Friedman, Shi-Hua Li, Xiao-Jiang Li

Conformational Diseases: Structural Studies of Aggregation of Polyglutamine Proteins

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 1 Year: 2011 Page: 23-43
Author(s): Elena Papaleo, Gaetano Invernizzi

Polyglutamine Protein Trafficking and Neurodegeneration

Journal: Current Genomics
Volume: 6 Issue: 3 Year: 2005 Page: 189-194
Author(s): John R. McGuire, Shi-Hua Li, Xiao-Jiang Li

Conformational Changes and Aggregation of Expanded Polyglutamine Proteins as Therapeutic Targets of the Polyglutamine Diseases: Exposed β-Sheet Hypothesis

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 3 Year: 2008 Page: 3267-3279
Author(s): Yoshitaka Nagai, H. Akiko Popiel

Peptide-Based Therapeutic Approaches for Treatment of the Polyglutamine Diseases

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 23 Year: 2014 Page: 2575-2582
Author(s): Toshihide Takeuchi,H. Akiko Popiel,Shiroh Futaki,Keiji Wada,Yoshitaka Nagai

Therapeutic Prospects for the Prevention of Neurodegeneration in Huntingtons Disease and the Polyglutamine Repeat Disorders

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 99-106
Author(s): Yoko Kimura, Wyan-Ching Mimi Lee, J. Troy Littleton

Expanding our Understanding of Polyglutamine Disease Through Transgenic Mice

Journal: Current Genomics
Volume: 2 Issue: 1 Year: 2001 Page: 27-39
Author(s): Jennifer D. Davidson, Harry T. Orr

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