Search Result "microsomal protein per gram of liver (MPPGL)"


Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution

Journal: Current Drug Metabolism
Volume: 11 Issue: 8 Year: 2010 Page: 678-685
Author(s): Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, Hiroshi Yamazaki

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Ontogeny of Hepatic Glucuronidation; Methods and Results

Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 728-743
Author(s): Elke H.J. Krekels, Meindert Danhof, Dick Tibboel, Catherijne A.J. Knibbe

Review Article

In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism

Journal: Current Drug Metabolism
Volume: 18 Issue: 11 Year: 2017 Page: 973-982
Author(s): Sung-min Choi,Chin-Yang Kang,Beom-Jin Lee,Jun-Bom Park

Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics

Journal: Drug Metabolism Letters
Volume: 9 Issue: 2 Year: 2015 Page: 80-87
Author(s): Shogo John Miyagi,Janel R. Long-Boyle

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