Search Result "microsomal clearance"


Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Applications of High Throughput Microsomal Stability Assay in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 6 Year: 2008 Page: 469-476
Author(s): Li Di, Edward H. Kerns, Xuewen JoAnn Ma, Youping Huang, Guy T. Carter

The Prediction of the Hepatic Clearance of Tanshinone IIA in Rat Liver Subcellular Fractions: Accuracy Improvement

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 39-45
Author(s): Guang-Ji Wang, Peng Li, Jing Li, Qian Zhang, Xin Liu, Alexander Khlentzos, Michael S. Roberts

Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Effect of Coenzyme Q10 on Warfarin Hydroxylation in Rat and Human Liver Microsomes

Journal: Current Drug Metabolism
Volume: 6 Issue: 2 Year: 2005 Page: 67-81
Author(s): Qingyu Zhou, Shufeng Zhou, Eli Chan

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

CYP1A1 Is a Major Enzyme Responsible for the Metabolism of Granisetron in Human Liver Microsomes

Journal: Current Drug Metabolism
Volume: 6 Issue: 5 Year: 2005 Page: 469-480
Author(s): H. Nakamura, N. Ariyoshi, K. Okada, H. Nakasa, K. Nakazawa, M. Kitada

In Vitro Microsomal Hepatic Metabolism of Antiasthmatic Prototype LASSBio-448

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1388-1398
Author(s): Isabelle Karine Costa Nunes,Luzineide Wanderley Tinoco,Helvecio Martins-Junior,Claudia Rezende,Eliezer J. Barreiro,Lidia Moreira Lima

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