Search Result "mechanistic approach to the design"


Using Structural and Mechanistic Information to Design Novel Inhibitors/Substrates of P-Glycoprotein

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1769-1774
Author(s): Freya Klepsch, Thomas Stockner, Thomas Erker, Markus Muller, Peter Chiba, Gerhard F. Ecker

Sulfur-based Mechanistic Probes for Enzyme-catalyzed Reactions

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 30 Year: 2013 Page: 3743-3758
Author(s): Weiping Zheng

Review Article

Rational Approaches, Design Strategies, Structure Activity Relationship and Mechanistic Insights for Esterase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 837-894
Author(s): Harbinder Singh,Jatinder Vir Singh,Navdeep Kaur,Mohit Sanduja,Gurpreet Singh,Preet Mohinder Singh Bedi,Sahil Sharma

Computational Approaches for Fragment-Based and De Novo Design

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 14-32
Author(s): Kathryn Loving, Ian Alberts, Woody Sherman

Fragment Based Drug Design: From Experimental to Computational Approaches

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 30 Year: 2012 Page: 5128-5147
Author(s): A. Kumar,A. Voet,K.Y.J. Zhang

Quality by Design (QbD) Approach in Pharmaceuticals: Status, Challenges and Next Steps

Journal: Drug Delivery Letters
Volume: 5 Issue: 1 Year: 2015 Page: 2-8
Author(s): Lalit Singh,Vijay Sharma

3D-QSAR Approaches in Drug Design: Perspectives to Generate Reliable CoMFA Models

Journal: Current Computer-Aided Drug Design
Volume: 10 Issue: 2 Year: 2014 Page: 148-159
Author(s): Cleber Camilo Melo-Filho,Rodolpho Campos Braga,Carolina Horta Andrade

Intestinal Targeting of Drugs: Rational Design Approaches and Challenges

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 776-802
Author(s): Kevin J. Filipski, Manthena V. Varma, Ayman F. El-Kattan, Catherine M. Ambler, Roger B. Ruggeri, Theunis C. Goosen, Kimberly O. Cameron

Ligand and Structure-Based Drug Design (LBDD and SBDD): Promising Approaches to Discover New Drugs

Ebook: Applied Computer-Aided Drug Design: Models and Methods
Volume: 1 Year: 2023
Author(s):
Doi: 10.2174/9789815179934123010003

Review Article

Advantages of Structure-Based Drug Design Approaches in Neurological Disorders

Journal: Current Neuropharmacology
Volume: 15 Issue: 8 Year: 2017 Page: 1136-1155
Author(s): Murali Aarthy,Umesh Panwar,Chandrabose Selvaraj,Sanjeev Kumar Singh

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