Search Result "mechanism based CYP inactivation"
High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points
Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 78-82
Author(s): Daniel Albaugh, Thomas Farrell, Michael Langan, W. George Lai
Oxypeucedanin is a Mechanism-based Inactivator of CYP2B6 and CYP2D6
Journal: Current Drug Metabolism
Volume: 22 Issue: 11 Year: 2021 Page: 882-892
Author(s): Kehan Zhang,Yilin Li,Yao Fu,Tiantian Cui,Qian Wang,Xu Mao,Ying Peng,Jiang Zheng
Molecular Analysis and Modeling of Inactivation of Human CYP2D6 by Four Mechanism Based Inactivators
Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 7-14
Author(s): Mara Livezey, Leslie D. Nagy, Laura E. Diffenderfer, Evan J. Arthur, David J. Hsi, Jeffrey M. Holton, Laura Lowe Furge
Enzyme Kinetics for Clinically Relevant CYP Inhibition
Journal: Current Drug Metabolism
Volume: 6 Issue: 3 Year: 2005 Page: 241-257
Author(s): Zhi-Yi Zhang, Y. Nancy Wong
Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf
Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Chemical Mechanisms, Structure-Activity Relationships and Relationship to Clinical Drug-Drug Interactions and Idiosyncratic Adverse Drug Reactions
Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 407-447
Author(s): Amit S. Kalgutkar, R. Scott Obach, Tristan S. Maurer
Therapeutic Drugs that Behave as Mechanism-Based Inhibitors of Cytochrome P450 3A4
Journal: Current Drug Metabolism
Volume: 5 Issue: 5 Year: 2004 Page: 415-442
Author(s): Shufeng Zhou, Eli Chan, Lee Yong Lim, Urs A. Boelsterli, Shu Chuen Li, Jiancheng Wang, Qiang Zhang, Min Huang, Anlong Xu
Drug-Drug Interactions via Mechanism-Based Cytochrome P450 Inactivation: Points to Consider for Risk Assessment from In Vitro Data and Clinical Pharmacologic Evaluation
Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 449-462
Author(s): Karthik Venkatakrishnan, R. Scott Obach
Potential Strategies for Minimizing Mechanism-Based Inhibition of Cytochrome P450 3A4
Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 990-1000
Author(s): Shu-Feng Zhou
Cytochrome P450 Enzymes Mechanism Based Inhibitors: Common Sub-Structures and Reactivity
Journal: Current Drug Metabolism
Volume: 6 Issue: 5 Year: 2005 Page: 413-451
Author(s): E. Fontana, P. M. Dansette, S. M. Poli