Search Result "lead optimization phase"
Advances in the Integration of Drug Metabolism into the Lead Optimization Paradigm
Journal: Mini-Reviews in Medicinal Chemistry
Volume: 9 Issue: 6 Year: 2009 Page: 703-716
Author(s): Walter A. Korfmacher
Exploring Natural Products as a Source for Antidiabetic Lead Compounds and Possible Lead Optimization
Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 23 Year: 2016 Page: 2549-2561
Author(s): Reema Abu Khalaf
Back to the Future: Lessons Learned in Modern Target-based and Whole-Cell Lead Optimization of Antimalarials
Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2012 Page: 473-483
Author(s): Arnab K. Chatterjee, Bryan K.S. Yeung
Application and Utilization of Chemoinformatics Tools in Lead Generation and Optimization
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 95-102
Author(s): N. Fotouhi, P. Gillespie, R. A. Goodnow, S.- S. So, Y. Han, L. E. Babiss
Computer-Aided Drug Design: Lead Discovery and Optimization
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 4 Year: 2012 Page: 328-337
Author(s): Mingli Xiang, Yu Cao, Wenjie Fan, Lijuan Chen, Yirong Mo
Structure Based Lead Optimization Approach in Discovery of Selective DPP4 Inhibitors
Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 6 Year: 2013 Page: 888-914
Author(s): Manjunath Ghate, Shailesh V. Jain
Novel, Acidic CCR2 Receptor Antagonists: Lead Optimization
Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 4 Year: 2007 Page: 263-271
Author(s): O. A. Dasse, J. L. Evans, H.-X. Zhai, D. Zou, J. T. Kintigh, F. Chan, K. Hamilton, E. Hill, J. B. Eckman, P. J. Higgins, A. Volosov, P. Collart, J.-M. Nicolas, R.K. Kondru, C.E. Schwartz
The In Silico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization
Journal: Current Medicinal Chemistry
Volume: 26 Issue: 2 Year: 2019 Page: 3838-3873
Author(s): Agostino Bruno,Gabriele Costantino,Luca Sartori,Marco Radi
Library Design Practices for Success in Lead Generation With Small Molecule Libraries
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 7 Year: 2003 Page: 649-660
Author(s): R. A. Goodnow Jr., W. Guba, W. Haap
Pharmacogenetics of Phase I and Phase II Drug Metabolism
Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 204-219
Author(s): Severine Crettol, Nenad Petrovic, Michael Murray